Robert Laumbach M.D., M.P.H., C.I.H.Associate Professor Rutgers University – School of Public HealthEOHSI – Clinical Research and Occupational Medicine
Current research interests are focused on two areas: 1) the interactive effects of exposure to multiple air pollutants and psychosocial stressors, and their cumulative impact on urban disparities in asthma, heart disease and cancer and 2) biological mechanisms underlying the effects of diesel exhaust and other air pollutants on pulmonary and cardiovascular disease. Approaches include community-based participatory research, controlled exposure studies, and semi-controlled “real-world” environmental exposure studies.
- Using controlled exposure to study interactions between exposure to diesel exhaust and psychological stress, we demonstrated that diesel exhaust can cause systemic “sickness response symptoms” in young healthy adults
- Using controlled exposure, we demonstrated that 1-aminopyrene may be a useful, specific biomarker for exposure to diesel exhaust.
- A simulated commuter car ride caused changes in cardiovascular function among volunteers with diabetes, measured as a decrease in heart rate variability at 24 hours after the ride
- Exposure to plume of dust and smoke from the 9/11 World Trade Center disaster was not associated with increased respiratory symptoms outside of the lower Manhattan area
- Development of collaborative relationships with stakeholders interested in applying scientific principles and knowledge to mitigate the environmental health problems and injustices in urban communities and communities adjacent to seaports in New Jersey.
- Promotion of science in public health policy in New Jersey through service on the New Jersey Department of Environmental Protection Science Advisory Board and New Jersey Clean Air Council.
- Thurston, GD, Kipen, H, Annesi-Maesano, I, Balmes, J, Brook, RD, Cromar, K, De Matteis, S, Forastiere, F, Forsberg, B, Frampton, MW et al.. A joint ERS/ATS policy statement: what constitutes an adverse health effect of air pollution? An analytical framework. Eur. Respir. J. 2017;49 (1):. doi: 10.1183/13993003.00419-2016. PubMed PMID:28077473
- Sunil, VR, Vayas, KN, Fang, M, Zarbl, H, Massa, C, Gow, AJ, Cervelli, JA, Kipen, H, Laumbach, RJ, Lioy, PJ et al.. World Trade Center (WTC) dust exposure in mice is associated with inflammation, oxidative stress and epigenetic changes in the lung. Exp. Mol. Pathol. 2017;102 (1):50-58. doi: 10.1016/j.yexmp.2016.12.005. PubMed PMID:27986442 PubMed Central PMC5472054
- Payne-Sturges, DC, Korfmacher, KS, Cory-Slechta, DA, Jimenez, M, Symanski, E, Carr Shmool, JL, Dotson-Newman, O, Clougherty, JE, French, R, Levy, JI et al.. Engaging Communities in Research on Cumulative Risk and Social Stress-Environment Interactions: Lessons Learned from EPA's STAR Program. Environ Justice. 2015;8 (6):203-212. doi: 10.1089/env.2015.0025. PubMed PMID:27688822 PubMed Central PMC4981147
- Patton, AP, Laumbach, R, Ohman-Strickland, P, Black, K, Alimokhtari, S, Lioy, P, Kipen, HM. Scripted drives: A robust protocol for generating exposures to traffic-related air pollution. Atmos Environ (1994). 2016;143 :290-299. doi: 10.1016/j.atmosenv.2016.08.038. PubMed PMID:27642251 PubMed Central PMC5019181
- Pettit, AP, Kipen, H, Laumbach, R, Ohman-Strickland, P, Kelly-McNeill, K, Cepeda, C, Fan, ZH, Amorosa, L, Lubitz, S, Schneider, S et al.. Disrupted Nitric Oxide Metabolism from Type II Diabetes and Acute Exposure to Particulate Air Pollution. PLoS ONE. 2015;10 (12):e0144250. doi: 10.1371/journal.pone.0144250. PubMed PMID:26656561 PubMed Central PMC4682772
- Mirowsky, JE, Peltier, RE, Lippmann, M, Thurston, G, Chen, LC, Neas, L, Diaz-Sanchez, D, Laumbach, R, Carter, JD, Gordon, T et al.. Repeated measures of inflammation, blood pressure, and heart rate variability associated with traffic exposures in healthy adults. Environ Health. 2015;14 :66. doi: 10.1186/s12940-015-0049-0. PubMed PMID:26276052 PubMed Central PMC4537534
- Laumbach, RJ. The Engine on the Bus Goes Vroom, Vroom, Vroom!. And the Fumes on the Bus Go . . ?. Am. J. Respir. Crit. Care Med. 2015;191 (12):1350-2. doi: 10.1164/rccm.201504-0836ED. PubMed PMID:26075420