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Photo of Frederick Kauffman Ph.D.
Frederick Kauffman, Ph.D.
Professor Emeritus Rutgers University – Ernest Mario School of PharmacyEOHSI – Toxicology

Research Areas

Biochemical Pharmacology and Toxicology. A major focus of work has been to define events regulating the metabolism of drugs and foreign chemicals in intact cells and tissues. Emphasis has been directed primarily at the metabolism of biologically active compounds via Phase II conjugation reactions. Recent research projects include: identifying isoforms of sulfotransferase and sulfatase in neural tissue, and investigating their possible involvement in modulating levels and activities of neuorsteroids in the central nervous system; and, secondly using a unique model of estrogen-dependent mammary tumors in ACI rats to explore relationships between the metabolism of estradiol and the occurrence and progression of hormone-dependent breast tumors.

Scholarly Activities

  • Fogarty Senior International Fellow, Department of Molecular Pathology, Ninewells Hospital and Medical School. University of Dundee, Scotland. Jan. 1995-Aug.1995, and subsequent summers 1996 and 1997.
  • Visiting Professor, Department of Pharmacology, Escola Paulista de Medicina. Sao Paulo, Brazil. December, 1993-Feb. 1994
  • Visiting Scholar, Howard Hughes Medical Institute, Duke University. Summer, 1988.

Recent Publications

  1. Mesia-Vela, S, Sanchez, RI, Roberts, KG, Reuhl, KR, Conney, AH, Kauffman, FC. Dietary clofibrate stimulates the formation and size of estradiol-induced breast tumors in female August-Copenhagen Irish (ACI) rats. Toxicology. 2008;246 (1):63-72. doi: 10.1016/j.tox.2007.12.025. PubMed PMID:18280627 PubMed Central PMC2441444
  2. Stakhiv, TM, Mesia-Vela, S, Kauffman, FC. Phase II antioxidant enzyme activities in brain of male and female ACI rats treated chronically with estradiol. Brain Res. 2006;1104 (1):80-91. doi: 10.1016/j.brainres.2006.05.093. PubMed PMID:16822482
  3. Mesia-Vela, S, Sanchez, RI, Reuhl, KR, Conney, AH, Kauffman, FC. Phenobarbital treatment inhibits the formation of estradiol-dependent mammary tumors in the August-Copenhagen Irish rat. J Pharmacol Exp Ther. 2006;317 (2):590-7. doi: 10.1124/jpet.105.096867. PubMed PMID:16421288
  4. Kauffman, FC. Sulfonation in pharmacology and toxicology. Drug Metab Rev. 2004;36 (3-4):823-43. doi: 10.1081/dmr-200033496. PubMed PMID:15554249
  5. Sanchez, RI, Mesia-Vela, S, Kauffman, FC. Induction of NAD(P)H quinone oxidoreductase and glutathione S-transferase activities in livers of female August-Copenhagen Irish rats treated chronically with estradiol: comparison with the Sprague-Dawley rat. J Steroid Biochem Mol Biol. 2003;87 (2-3):199-206. doi: 10.1016/j.jsbmb.2003.08.007. PubMed PMID:14672740
  6. Mesia-Vela, S, Sanchez, RI, Li, JJ, Li, SA, Conney, AH, Kauffman, FC. Catechol estrogen formation in liver microsomes from female ACI and Sprague-Dawley rats: comparison of 2- and 4-hydroxylation revisited. Carcinogenesis. 2002;23 (8):1369-72. doi: 10.1093/carcin/23.8.1369. PubMed PMID:12151356
  7. Pignatello, MA, Kauffman, FC, Levin, AA. Liarozole markedly increases all trans-retinoic acid toxicity in mouse limb bud cell cultures: a model to explain the potency of the aromatic retinoid (E)-4-[2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthylenyl)-1-propenyl] benzoic acid. Toxicol Appl Pharmacol. 2002;178 (3):186-94. doi: 10.1006/taap.2001.9340. PubMed PMID:11858735
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Photo of Georgios Kelesidis Ph.D.
Georgios Kelesidis, Ph.D.
Assistant Professor Rutgers UniversityEOHSI Division of Environmental and Population Health Biosciences

Biographical Info

Dr. Kelesidis is an Assistant Professor at the Rutgers University School of Public Health. He received his Diploma in Chemical Engineering from University of Patras (Greece), a M.Sc. and a Ph.D. in Mechanical and Process Engineering from ETH Zurich (Switzerland). Before joining Rutgers University, he was a lecturer and research associate at the Particle Technology Laboratory of ETH Zurich (Switzerland).

Research Areas

The research of Dr. Kelesidis focuses on the climate and public health impact of carbonaceous aerosols. To this end, he has developed advanced computational algorithms during his M.Sc. and Ph.D. studies that simulate in detail the morphology, optical properties and climate forcing of organic and black carbon (soot) nanoparticles. His models were able to explain several observations made over the past 20 years in various laboratories across the world. In collaboration with Siemens AG, these models have been used for the design of robust laser diagnostics (e.g. smoke detectors) for fast detection and prevention of fires. His recent research involves the design of novel platforms for the controlled, high-throughput aerosol synthesis of carbonaceous nanoparticles that emulate real world emissions. This enables the detailed physicochemical and toxicological characterization of such pollutants and facilitates the accurate estimation and mitigation of their contribution to global warming. The aerosol-based platforms developed here are also used for the design of functional nanomaterials with superior performance in energy, sensor and biomedical applications.

The 2015 M.Sc. thesis of Dr. Kelesidis at ETH Zurich earned the IBM research prize (2017) for computer modelling and simulations in chemistry, biology and material science. His 2019 Ph.D. thesis on the morphology and optical properties of flame-made nanoparticles received the 2020 Ph.D. Award from GAeF (German Association for Aerosol Research) and the ETH medal for Outstanding Doctoral Thesis (top 8 %). He received also the 1st Graduate Student Award on Carbon Nanomaterials at the 2019 AIChE Annual Meeting (Orlando, FL, USA), as well as Best Poster Awards at the European Aerosol Conference in 2016 (Tours, France) and 2020 (Aachen, Germany), the 2019 ETH Conference on Combustion Generated Nanoparticles (Zürich, Switzerland) and the 2019 Fall Meeting of the Material Research Society. The societal impact of his Ph.D. research was also highlighted by the Forbes Magazine by including him in the 2020 Forbes 30 under 30 Europe list for Science & Healthcare. He has co-authored 21 peer-reviewed articles so far, being the first author in 16 of them.

Research Highlights

  • Advanced computational algorithms for the morphology (doi.org/10.1016/j.carbon.2017.06.004), optical properties (doi.org/10.1016/j.proci.2018.08.025) and climate impact (doi.org/10.1021/acs.est.2c00428) of carbonaceous aerosols.
  • High-throughput, aerosol synthesis and physicochemical characterization of organic (doi.org/10.1080/02786826.2022.2070055) and inorganic (doi.org/10.1021/acs.langmuir.8b00576) nanomaterials.
  • Design of laser diagnostics (e.g. smoke detectors) for fire detection & prevention (doi.org/10.1016/j.powtec.2019.02.003).
  • Optimization of nanoparticle size, morphology and porosity for energy (doi.org/10.1016/j.carbon.2022.06.020), sensor (doi.org/10.1021/acs.analchem.1c05145) and biomedical (doi.org/10.1021/acsnano.7b05518) applications.

Scholarly Activities

  • Member of the leadership team on Laminar Flames and Chemistry and Particle Formation of the International Sooting Flame Workshop.
  • Co-chair of the Aerosol Technology Working Group of the European Aerosol Assembly.
  • Session chair for the 2019-2021 European (EAC) and 2022 International Aerosol Conferences (IAC), the 2020-2022 Annual Conferences of the American Association for Aerosol Research (AAAR), the 2022 World Congress on Particle Technology and the 2016 Fall Meeting of the Material Research Society.

Publications

  • Kelesidis, G.A., Crepaldi, P., Allemann, M., Duric, A. and Pratsinis, S.E., “The mobility diameter of soot determines its angular light scattering distribution”, Combustion and Flame, (2023) accepted; doi: 10.1016/j.combustflame.2022.112476.
  • Kelesidis, G.A., Rossi, N. and Pratsinis, S.E., “Porosity and crystallinity dynamics of carbon black during internal and surface oxidation”, Carbon 197, 334-340 (2022).

3 min talk @ 6th International Sooting Flame Workshop, Vancouver, Canada (Best 3-min presentation award).

12 min talk @ 11th International Aerosol Conference, Athens, Greece.

  • Kelesidis, G.A., Neubauer, D., Fan, L.-S., Lohmann, U. and Pratsinis, S.E., “Enhanced direct radiative forcing by black carbon agglomerates”, Environmental Science and Technology 56, 8610-8618 (2022).

11 min talk @ 39th Annual (Virtual) Conference of the American Association for Aerosol Research (AAAR).

  • Trivanovic, U., Kelesidis, G.A. and Pratsinis, S.E., “High-throughput generation of aircraft-like soot”, Aerosol Science and Technology 56, 732-743 (2022).
  • Kelesidis, G.A., Gao, D., Starsich, F.H.L. and Pratsinis, S.E., “Light extinction by agglomerates of gold nanoparticles: A plasmon ruler for sub-10 nm interparticle distances”, Analytical Chemistry 94, 5310-5316 (2022).
  • Kelesidis, G.A. and Pratsinis, S.E., “Santoro flame: the volume fraction of soot accounting for its morphology and composition”, Combustion and Flame, 240, 112025-1-5 (2022).

12 min talk @ 39th Annual (Virtual) Conference of the American Association for Aerosol Research (AAAR).

  • Kelesidis, G.A. and Pratsinis, S.E., “A perspective on gas-phase synthesis of nanomaterials: Process design, impact and outlook”, Chemical Engineering Journal 421, 129884-1-7 (2021).
  • Kelesidis, G.A. and Kholghy, M.R., “A Monodisperse Population Balance Model for Nanoparticle Agglomeration in the Transition Regime”, Materials 14, 3882-1-13 (2021).
  • Kelesidis, G.A. and Pratsinis, S.E., “Determination of the volume fraction of soot accounting for its composition and morphology”, Proc. of the Combustion Institute 38, 1189-1196 (2021).

15 min talk @ 2021 International Symposium on Combustion (Virtual), Adelaide, Australia.

  • Kelesidis, G.A. and Goudeli, E., “Self-preserving size distribution and collision frequency of flame-made nanoparticles in the transition regime”, Proc. of the Combustion Institute 38, 1233-1240 (2021).
  • Kelesidis, G.A., Bruun, A. and Pratsinis, S.E., “The impact of organic carbon on soot light absorption”, Carbon, 172, 742-749 (2021).

3 min talk @ 2020 European Aerosol Conference (Virtual), Aachen, Germany (Best Poster Award).

  • Kholghy, M.R. and Kelesidis, G.A., “Surface growth, coagulation and oxidation of soot by a monodisperse population balance model”, Combustion and Flame, 227, 456-463 (2021).
  • Kelesidis, G.A., Kholghy, M.R., Zuercher, J., Robertz, J., Allemann, M., Duric, A. and Pratsinis, S.E., “Light scattering from nanoparticle agglomerates”, Powder Technology 365, 52-59 (2020).
  • Kelesidis, G.A. and Pratsinis, S.E., “Soot light absorption and refractive index during agglomeration and surface growth”, Proc. of the Combustion Institute 37, 1177-1184 (2019).
  • Kelesidis, G.A. and Pratsinis, S.E., “Estimating the internal and surface oxidation of soot agglomerates”, Combustion and Flame 209, 493-499 (2019).

3 min talk @ 2020 European Aerosol Conference (Virtual), Aachen, Germany.

  • Kelesidis, G.A., Furrer, F.M., Wegner, K. and Pratsinis, S.E., “Impact of humidity on silica nanoparticle agglomerate morphology and size distribution”, Langmuir 34, 8532-8541 (2018).

12 min talk @ 2020 European Aerosol Conference (Virtual), Aachen, Germany.

  • Kholghy, M.R., Kelesidis, G.A. and Pratsinis, S.E., “Reactive polycyclic aromatic hydrocarbon dimerization drives soot nucleation”, Physical Chemistry Chemical Physics 20, 10926-10938 & Erratum, ibid 20, 28941-28942 (2018).
  • Kelesidis, G.A., Goudeli, E. and Pratsinis, S.E., “Morphology and Mobility Diameter of Carbonaceous Aerosols by Agglomeration and Surface Growth”, Carbon 121, 527-535 (2017).
  • Pratsinis, A., Kelesidis, G.A., Zuercher, S., Krumeich, F., Bolisetty, S., Mezzenga, R., Leroux, J.C. and Sotiriou, G.A., “Enzyme-mimetic antioxidant luminescent nanoparticles for highly sensitive hydrogen peroxide biosensing”, ACS Nano 11, 12210-12218 (2017).
  • Kelesidis, G.A., Goudeli, E. and Pratsinis, S.E., “Flame synthesis of functional materials and devices: Surface growth and aggregation”, Proc. of the Combustion Institute 36, 29-50 (2017).
  • Dimakopoulos, Y., Kelesidis, G.A., Tsouka, S., Georgiou, G.C. and Tsamopoulos, J., “Hemodynamics in stenotic vessels of small diameter under steady state conditions: Effect of viscoelasticity and migration of red blood cells”, Biorheology 52, 183-210 (2015).

 

Eunchong (Joe) Kim
Laboratory Manager Rutgers UniversityEOHSI – Pharmacology and Toxicology
Photo of Howard Kipen MPH. MD
Howard Kipen, MPH. MD
Professor, Department of Occupational and Environmental Health Rutgers University – School of Public HealthEOHSI – Director, Clinical Research and Occupational Medicine

Dr. Kipen received his BA from UC Berkeley and his MD from UC San Francisco and MPH from Columbia University.  He completed an internal medicine residency at the Columbia-Presbyterian Medical Center, and a fellowship at Mount Sinai Medical  Center, Environmental Sciences Laboratory, in Manhattan.

Research Areas

Dr. Kipen’s research focuses on clinical and epidemiological studies of the health effects of ambient and indoor air pollution. He works closely with Rob Laumbach of the CROM division as well as Debra Laskin and Andrew Gow of Toxicology. They use both controlled human  exposure models and real-world clinical studies to develop and test mechanistic biomarkers of air pollution toxicity. Concentrating on biomarkers of cardiopulmonary effects, prior studies have examined fresh diesel exhaust and secondary organic aerosols. We are currently studying effects of controlled ozone exposures on macrophage phenotypes in induced sputum.   Working in the real world, we have examined cardiopulmonary and oxidative stress outcomes in highway passengers who were driven in a diesel-enriched enriched environment. More recently we examined the ability of portable air cleaners to reduce indoor particulate air pollution and consequent biomarkers of cardiopulmonary health in elderly apartment dwellers.   In light of the current pandemic we have used our experience measuring and filtering particulates in homes to examine SARS-coV-2  aerosols in patient homes.  A more recent interest is to explore underlying mechanisms for the robust human finding of acute cognitive impairment from inhaled CO2 at commonly encountered levels.

Research Highlights

With former EOHSI members Jim Zhang and David Rich, we conducted a panel study of 130 Beijing medical students built around the Chinese Government’s drastic reductions in air pollution during the 2008 Olympics. We observed broad declines in multiple oxidative stress, inflammatory, and platelet activation biomarkers. Major results have been published in JAMA and the American Journal of Respiratory and Critical Care Medicine with multiple subsidiary papers and a complete report published by the Health Effects Institute. We have Analogous increases in vascular and pulmonary oxidative stress  have ben demonstrated after a 90 minute ride on the NJ Turnpike. Similar findings have been found using controlled exposure to fresh diesel exhaust iin our controlled environment  facility. Related effects have been shown with New Jersey air pollution on the Turnpike and are being evaluated with air cleaners in individual homes.

Significant declines in proteasome (UPP) activity after exposure to secondary organic aerosol and diesel exhaust were observed immediately following exposure in healthy subjects, although our prior work did not reveal apparent nasal inflammatory effects from acute exposures to secondary organic aerosol. The above declines in proteasome activity showed a significant interaction (3-fold increase) in subjects with the ILE/ILE polymorphism of GSTP1.

Scholarly Activities

  • Chair, NASA Human Research Program’s Advanced Environmental Health / Advanced Food Technology Standing Review Panel (2015-2018)
  • Chair, Scientific Assembly on Environmental, Occupational, and Population Health, American Thoracic Society (2017-2019)
  • Member, National Academies Standing Committee on Medical and Epidemiological Aspects of Air Pollution on U.S. Government Employees and their Families, 2016-2021.
  • Director, Integrated Health Sciences Facility Core, Rutgers Center for Environmental Exposures and Disease (CEED), NIEHS
  • Chair / Member Multiple Ad Hoc Grant Review Panels (e.g., NIEHS, Department of Defense)
  • Governor’s Appointee, Public Employee’s Occupational Safety and Health Review Commission, New Jersey Department of Labor
  • Member, Public Health Scientific Advisory Board, New Jersey Department of Environmental Protection

Howard Kipen’s Publications

Recent Publications

  1. Ji N, Fang M1. 11.Baptista A, Cepeda C, Greenberg M, Mincey IC, Ohman-Strickland P, Haynes F, Fiedler N, Kipen HM, Laumbach RJ. Exposure to traffic-related airpollution and changes in exhaled nitric oxide and DNA methylation in arginase andnitric oxide synthase in children with asthma. Environ Health. 2021 Feb 11; 20(1):12. doi: 10.1186/s12940-020-00678-8. PMID: 33573660; PMCID: PMC7879528
  2. Laumbach RJ, Mainelis G, Black KG, Myers NT, Ohman-Strickland P, Alimokhtari S, Hastings S, Legard A, De Resende A, Calderón L, Lu FT, Kipen HM. Presence of SARS-CoV-2 Aerosol in Residences of Adults with COVID-19. Ann Am Thorac Soc. 2021 Nov 11. doi: 10.1513/AnnalsATS.202107-847RL. Epub ahead of print. PMID: 34762562.
  3. Hussain, S., Laumbach, R., Coleman, J., Youssef, H., Kelly-McNeil, K., Ohman-Strickland, P., Zhang, J., & Kipen, H.M. Controlled Exposure to Diesel Exhaust Causes Increased Nitrite in Exhaled Breath Condensate among Subjects with Asthma.  J Occup Environ Med 54(10): 1186-91, Oct 2012. PMCID: PMC4443752

Other Publications

  1. Yang, Z, Black, K, Ohman-Strickland, P, Graber, JM, Kipen, HM, Fang, M, Zarbl, H. Disruption of central and peripheral circadian clocks and circadian controlled estrogen receptor rhythms in night shift nurses in working environments. FASEB J. 2024;38 (11):e23719. doi: 10.1096/fj.202302261RR. PubMed PMID:38837828
  2. Lu, FT, Laumbach, RJ, Legard, A, Myers, NT, Black, KG, Ohman-Strickland, P, Alimokhtari, S, de Resende, A, Calderón, L, Mainelis, G et al.. Real-World Effectiveness of Portable Air Cleaners in Reducing Home Particulate Matter Concentrations. Aerosol Air Qual Res. 2024;24 (1):. doi: 10.4209/aaqr.230202. PubMed PMID:38618024 PubMed Central PMC11014421
  3. Caruth, J, Black, K, Legard, A, De Resende, A, Getz, K, Borowski, M, Debilio, L, Brewer, A, Kipen, H, Udasin, IG et al.. Incidence and Predictors of COVID-19 Infection in Prison Healthcare Workers. J Occup Environ Med. 2023;65 (7):573-579. doi: 10.1097/JOM.0000000000002836. PubMed PMID:36882811 PubMed Central PMC10329989
  4. Gholizadeh, A, Black, K, Kipen, H, Laumbach, R, Gow, A, Weisel, C, Javanmard, M. Detection of respiratory inflammation biomarkers in non-processed exhaled breath condensate samples using reduced graphene oxide. RSC Adv. 2022;12 (55):35627-35638. doi: 10.1039/d2ra05764f. PubMed PMID:36545081 PubMed Central PMC9745889
  5. Myers, NT, Laumbach, RJ, Black, KG, Ohman-Strickland, P, Alimokhtari, S, Legard, A, De Resende, A, Calderón, L, Lu, FT, Mainelis, G et al.. Portable air cleaners and residential exposure to SARS-CoV-2 aerosols: A real-world study. Indoor Air. 2022;32 (4):e13029. doi: 10.1111/ina.13029. PubMed PMID:35481935 PubMed Central PMC9111720
  6. Laumbach, RJ, Mainelis, G, Black, KG, Myers, NT, Ohman-Strickland, P, Alimokhtari, S, Hastings, S, Legard, A, de Resende, A, Calderón, L et al.. Presence of SARS-CoV-2 Aerosol in Residences of Adults with COVID-19. Ann Am Thorac Soc. 2022;19 (2):338-341. doi: 10.1513/AnnalsATS.202107-847RL. PubMed PMID:34762562 PubMed Central PMC8867362
  7. Zhang, JJ, Kan, H, Kipen, HM. Respiratory health, children’s lung function, and air quality in four Chinese cities: two snapshots in 1993-1996 and 2017-2018. J Thorac Dis. 2020;12 (10):6311-6314. doi: 10.21037/jtd-19-crh-aq-preface. PubMed PMID:33209470 PubMed Central PMC7656390
  8. Malaviya, R, Kipen, HM, Businaro, R, Laskin, JD, Laskin, DL. Pulmonary toxicants and fibrosis: innate and adaptive immune mechanisms. Toxicol Appl Pharmacol. 2020;409 :115272. doi: 10.1016/j.taap.2020.115272. PubMed PMID:33031836 PubMed Central PMC9960630
  9. Radbel, J, Laskin, DL, Laskin, JD, Kipen, HM. Disease-modifying treatment of chemical threat agent-induced acute lung injury. Ann N Y Acad Sci. 2020;1480 (1):14-29. doi: 10.1111/nyas.14438. PubMed PMID:32726497 PubMed Central PMC10250775
  10. Kipen, HM, Laskin, DL. NETs: a new biomarker of traffic-related air pollution exposure: are they ready to catch fish?. Eur Respir J. 2020;55 (4):. doi: 10.1183/13993003.00305-2020. PubMed PMID:32245775 PubMed Central PMC10250776
  11. Sunil, VR, Radbel, J, Hussain, S, Vayas, KN, Cervelli, J, Deen, M, Kipen, H, Udasin, I, Laumbach, R, Sunderram, J et al.. Sarcoid-Like Granulomatous Disease: Pathologic Case Series in World Trade Center Dust Exposed Rescue and Recovery Workers. Int J Environ Res Public Health. 2019;16 (5):. doi: 10.3390/ijerph16050815. PubMed PMID:30845693 PubMed Central PMC6427752
  12. Chiao, S, Kipen, H, Hallman, WK, Pollio, DE, North, CS. Anthrax Exposure, Belief in Exposure, and Postanthrax Symptoms Among Survivors of a Bioterrorist Attack on Capitol Hill. Disaster Med Public Health Prep. 2019;13 (3):555-560. doi: 10.1017/dmp.2018.115. PubMed PMID:30417804
  13. Fiedler, N, Weisel, C, Nwankwo, C, Kipen, H, Lange, G, Ohman-Strickland, P, Laumbach, R. Chronic Exposure to Solvents Among Construction Painters: Reductions in Exposure and Neurobehavioral Health Effects. J Occup Environ Med. 2018;60 (12):e663-e670. doi: 10.1097/JOM.0000000000001470. PubMed PMID:30308619 PubMed Central PMC6289817
  14. Gholizadeh, A, Voiry, D, Weisel, C, Gow, A, Laumbach, R, Kipen, H, Chhowalla, M, Javanmard, M. Toward point-of-care management of chronic respiratory conditions: Electrochemical sensing of nitrite content in exhaled breath condensate using reduced graphene oxide. Microsyst Nanoeng. 2017;3 :17022. doi: 10.1038/micronano.2017.22. PubMed PMID:31057865 PubMed Central PMC6444995
  15. Thurston, GD, Kipen, H, Annesi-Maesano, I, Balmes, J, Brook, RD, Cromar, K, De Matteis, S, Forastiere, F, Forsberg, B, Frampton, MW et al.. A joint ERS/ATS policy statement: what constitutes an adverse health effect of air pollution? An analytical framework. Eur Respir J. 2017;49 (1):. doi: 10.1183/13993003.00419-2016. PubMed PMID:28077473 PubMed Central PMC5751718
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Photo of Ah-Ng Tony Kong Ph.D.
Ah-Ng Tony Kong, Ph.D.
Glaxo Endowed Chair in Pharmaceutics; Graduate Director Rutgers UniversityErnest Mario School of Pharmacy

 

Grants/FundingDr. Kong is currently funded by NIH R01CA200129, R01AT007065 and R01AT009152.
Education & TrainingPhD – Pharmaceutics, Pharmacokinetics and Pharmacodynamics – State University of New York, Buffalo, NY
BS – Pharmacy with First Class Standing – University of Alberta, Canada
Post-Doctoral Fellowship – Molecular Biology of Phase I/Phase II Drug Metabolizing Enzymes – National Institutes of Health
Post-Doctoral Fellowship – Cellular and Molecular Signaling of T-cell Activation – National Institutes of Health
Research InterestsNatural & Botanical Products Drug Discovery & Development, Epigenetics/epigenomics of oxidative stress/inflammation induced diseases including cancer and their prevention/treatment with botanicals/phytochemicals/drugs, Nrf2-mediated anti-oxidative stress/inflammation, Pharmacokinetics (PK)/pharmacodynamics (PD) studies and modeling. Dr. Kong’s current research focuses on, 1) Studies of botanical/dietary/herbal medicinal phytochemicals-mediated epigenetics/epigenomics signaling and diseases prevention such as cancer chemoprevention, 2) Nrf2-mediated redox signaling in anti-oxidative stress, anti-inflammatory, and Phase II drug metabolizing enzymes (DME) /Phase III transporters, 3) Pharmacokinetics (PK)/ pharmacodynamics (PD) studies and PKPD modeling of botanicals/dietary phytochemicals/drugs. Dr. Kong is currently funded by NIH R01CA200129, and R01AT009152.
Scholarly Activities– Member, President’s Committee on Academic Program (CAPR)
– Director of the Graduate Program in Pharmaceutical Sciences
– Founding Editor-in-Chief, Current Pharmacology Reports (Springer)
– Serving on NIH study section panels

Publications

Awards2018 – Clarivate Analytics (formerly Thomson Reuters) Highly Cited Researcher – among an elite group recognized for exceptional research performance demonstrated by production of multiple highly cited papers that rank in the top 1% by citations for field and year in Web of Science.
2018 – Overseas Visiting Professor, Khon Kaen University, Khon Kaen, Thailand.
2016 – Fellow (Elected), American Association for the Advancement of Science (AAAS)
2014 – Thomson Reuters Highly Cited Researcher – in recognition of ranking among the top 1% of researchers for most cited documents, in Pharmacology and Toxicology
2013 – Visiting Professor, Guangzhou University of Chinese Medicine, Guangzhou, China
2012 – Visiting Professor, Southern Medical University, Guangzhou, China
2011 – Guest Professor, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing, China
2009-2013 – Elected Member-at-Large, American Association for the Advancement of Science (AAAS)
2004 – Fellow (Elected), American Association of Pharmaceutical Scientists (AAPS)
2003 – Alumni Association Distinguished Visitor” under the Alumni Association Rotating Visiting Professorship Program, The King Edward VII College of Medicine and The Faculties of Medicine, Universities of Malaya and Singapore
1998 – Recognized by the American Association of Colleges of Pharmacy as Teacher of the Year
1998 – “Outstanding Teacher of the Year Award” from the first professional year class, University of Illinois at Chicago College of Pharmacy
1996 – “Outstanding Teacher of the Year Award” from the first professional year class, University of Illinois at Chicago College of Pharmacy
1994 – Young Investigator Award in Pharmacokinetics, Pharmacodynamics and Drug Metabolism from the American Association of Pharmaceutical Scientists (AAPS), Sponsored by Burroughs Wellcome Fund

 

Photo of Bo Kong Ph.D.
Bo Kong, Ph.D.
Rutgers UniversityEOHSI – Exposure Science and Epidemiology

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