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Ah-Ng Tony Kong, Ph.D.
Glaxo Endowed Chair in Pharmaceutics
Graduate Director
Ernest Mario School of Pharmacy
Environmental and Occupational Health Sciences Institute
Rutgers University
Room 226
160 Frelinghuysen Road, Piscataway, NJ 08854
Work Phone: 848-445-6368 (office)
Work Email:
BS – Pharmacy with First Class Standing – University of Alberta, Canada
Post-Doctoral Fellowship – Molecular Biology of Phase I/Phase II Drug Metabolizing Enzymes – National Institutes of Health
Post-Doctoral Fellowship – Cellular and Molecular Signaling of T-cell Activation – National Institutes of Health
Research Areas
- Natural & Botanical Products Drug Discovery & Development,
- Epigenetics/epigenomics of oxidative stress/inflammation induced diseases including cancer and their prevention/treatment with botanicals/phytochemicals/drugs, Nrf2-mediated anti-oxidative stress/inflammation,
- Pharmacokinetics (PK)/pharmacodynamics (PD) studies and modeling. Dr. Kong’s current research focuses on,
- 1) Studies of botanical/dietary/herbal medicinal phytochemicals-mediated epigenetics/epigenomics signaling and diseases prevention such as cancer chemoprevention,
- 2) Nrf2-mediated redox signaling in anti-oxidative stress, anti-inflammatory, and Phase II drug metabolizing enzymes (DME) /Phase III transporters, 3) Pharmacokinetics (PK)/ pharmacodynamics (PD) studies and PKPD modeling of botanicals/dietary phytochemicals/drugs. Dr. Kong is currently funded by NIH R01CA200129, and R01AT009152
Scholarly Activities
- Member, President’s Committee on Academic Program (CAPR)
- Director of the Graduate Program in Pharmaceutical Sciences
- Founding Editor-in-Chief, Current Pharmacology Reports (Springer)
- Serving on NIH study section panels
Scholarly Activities
- 2018 – Clarivate Analytics (formerly Thomson Reuters) Highly Cited Researcher – among an elite group recognized for exceptional research performance demonstrated by production of multiple highly cited papers that rank in the top 1% by citations for field and year in Web of Science.
- 2018 – Overseas Visiting Professor, Khon Kaen University, Khon Kaen, Thailand.
- 2016 – Fellow (Elected), American Association for the Advancement of Science (AAAS)
- 2014 – Thomson Reuters Highly Cited Researcher – in recognition of ranking among the top 1% of researchers for most cited documents, in Pharmacology and Toxicology
- 2013 – Visiting Professor, Guangzhou University of Chinese Medicine, Guangzhou, China
- 2012 – Visiting Professor, Southern Medical University, Guangzhou, China
- 2011 – Guest Professor, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing, China
- 2009-2013 – Elected Member-at-Large, American Association for the Advancement of Science (AAAS)
- 2004 – Fellow (Elected), American Association of Pharmaceutical Scientists (AAPS)
- 2003 – Alumni Association Distinguished Visitor” under the Alumni Association Rotating Visiting Professorship Program, The King Edward VII College of Medicine and The Faculties of Medicine, Universities of Malaya and Singapore
- 1998 – Recognized by the American Association of Colleges of Pharmacy as Teacher of the Year
- 1998 – “Outstanding Teacher of the Year Award” from the first professional year class, University of Illinois at Chicago College of Pharmacy
- 1996 – “Outstanding Teacher of the Year Award” from the first professional year class, University of Illinois at Chicago College of Pharmacy
- 1994 – Young Investigator Award in Pharmacokinetics, Pharmacodynamics and Drug Metabolism from the American Association of Pharmaceutical Scientists (AAPS), Sponsored by Burroughs Wellcome Fund
Recent Publications
- Mesia-Vela, S, Sanchez, RI, Roberts, KG, Reuhl, KR, Conney, AH, Kauffman, FC. Dietary clofibrate stimulates the formation and size of estradiol-induced breast tumors in female August-Copenhagen Irish (ACI) rats. Toxicology. 2008;246 (1):63-72. doi: 10.1016/j.tox.2007.12.025. PubMed PMID:18280627 PubMed Central PMC2441444
- Stakhiv, TM, Mesia-Vela, S, Kauffman, FC. Phase II antioxidant enzyme activities in brain of male and female ACI rats treated chronically with estradiol. Brain Res. 2006;1104 (1):80-91. doi: 10.1016/j.brainres.2006.05.093. PubMed PMID:16822482
- Mesia-Vela, S, Sanchez, RI, Reuhl, KR, Conney, AH, Kauffman, FC. Phenobarbital treatment inhibits the formation of estradiol-dependent mammary tumors in the August-Copenhagen Irish rat. J Pharmacol Exp Ther. 2006;317 (2):590-7. doi: 10.1124/jpet.105.096867. PubMed PMID:16421288
- Kauffman, FC. Sulfonation in pharmacology and toxicology. Drug Metab Rev. 2004;36 (3-4):823-43. doi: 10.1081/dmr-200033496. PubMed PMID:15554249
- Sanchez, RI, Mesia-Vela, S, Kauffman, FC. Induction of NAD(P)H quinone oxidoreductase and glutathione S-transferase activities in livers of female August-Copenhagen Irish rats treated chronically with estradiol: comparison with the Sprague-Dawley rat. J Steroid Biochem Mol Biol. 2003;87 (2-3):199-206. doi: 10.1016/j.jsbmb.2003.08.007. PubMed PMID:14672740
- Mesia-Vela, S, Sanchez, RI, Li, JJ, Li, SA, Conney, AH, Kauffman, FC. Catechol estrogen formation in liver microsomes from female ACI and Sprague-Dawley rats: comparison of 2- and 4-hydroxylation revisited. Carcinogenesis. 2002;23 (8):1369-72. doi: 10.1093/carcin/23.8.1369. PubMed PMID:12151356
- Pignatello, MA, Kauffman, FC, Levin, AA. Liarozole markedly increases all trans-retinoic acid toxicity in mouse limb bud cell cultures: a model to explain the potency of the aromatic retinoid (E)-4-[2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthylenyl)-1-propenyl] benzoic acid. Toxicol Appl Pharmacol. 2002;178 (3):186-94. doi: 10.1006/taap.2001.9340. PubMed PMID:11858735
Categories: Faculty, Toxicology
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