Professor – Pharmacology and Toxicology
Ernest Mario School of PharmacyEOHSI – Toxicology Division
Work Phone: 848-445-5518 (office)work
Work Phone: 848-445-0187 (lab)work
Work Email: aleksunes@eohsi.rutgers.eduINTERNET
Biography
Lauren Aleksunes’Lab
Recent Publications
- Henry, ZR, Armstrong, L, Maliha, S, Jia, X, Gao, S, Taylor, RE, Basaly, V, Otersen, K, Yang, Z, Rizzolo, D et al.. Deletion of hepatic FXR leads to more severe MASH development in female mice. Hepatol Commun. 2025;9 (6):. doi: 10.1097/HC9.0000000000000693. PubMed PMID:40377496 PubMed Central PMC12088634
- Wang, T, Jia, X, Aleksunes, LM, Shen, H, Deng, HW, Zhu, H. Developmental toxicity: artificial intelligence-powered assessments. Trends Pharmacol Sci. 2025; :. doi: 10.1016/j.tips.2025.04.005. PubMed PMID:40374415
- Rivera-Núñez, Z, Kinkade, C, Brinker, A, Zhang, R, Buckley, B, Brunner, J, Ohman-Strickland, P, Qiu, X, Qasem, RJ, Fallon, JK et al.. Mycoestrogen Exposure during Pregnancy: Impact of the ABCG2 Q141K Variant on Birth and Placental Outcomes. Environ Health Perspect. 2025;133 (5):57001. doi: 10.1289/EHP14478. PubMed PMID:40126888 PubMed Central PMC12052082
- Asby, SC, Thompson, LE, Goedken, M, Lucia, SM, Dominguez, AT, Kar, A, Pitts, TM, Kiseljak-Vassiliades, K, Lang, J, Aleksunes, LM et al.. Pathological findings of immunotherapy-induced nephrotoxicity in a humanized immune system mouse model. Kidney Int. 2025;107 (5):930-934. doi: 10.1016/j.kint.2025.01.021. PubMed PMID:39922378
- Thompson, LE, Ghimire, A, Wen, X, Kim, C, Choza, J, Doherty, CL, Buckley, BT, Bowles, DW, O’Bryant, CL, Pfister, DG et al.. A Pharmacokinetic/Toxicodynamic Model of Cisplatin Nephrotoxicity Using the Kidney Injury Molecule-1 Biomarker. J Pharmacol Clin Toxicol. 2024;12 (1):. doi: 10.47739/pharmacology1184. PubMed PMID:39726772 PubMed Central PMC11671133
- Thompson, LE, Ghimire, A, Wen, X, Kim, C, Doherty, CL, Buckley, BT, Bowles, DW, O’Bryant, CL, Jaimes, EA, Aleksunes, LM et al.. Population Pharmacokinetic Model of Platinum Disposition in Cancer Patients Receiving Cisplatin and Randomized to 5-HT3 Antagonist Antiemetic Drugs. J Clin Pharmacol. 2024; :. doi: 10.1002/jcph.6177. PubMed PMID:39711135
- Toth, E, Li, H, Frost, K, Sample, P, Jilek, J, Greenfield, S, You, D, Kozlosky, D, Goedken, M, Paine, MF et al.. Nonalcoholic steatohepatitis increases plasma retention of sorafenib-glucuronide in a mouse model by altering hepatocyte hopping. Acta Pharm Sin B. 2024;14 (11):4874-4882. doi: 10.1016/j.apsb.2024.09.004. PubMed PMID:39664440 PubMed Central PMC11628858
- Kinkade, CW, Rivera-Núñez, Z, Brinker, A, Buckley, B, Waysack, O, Kautz, A, Meng, Y, Ohman Strickland, P, Block, R, Groth, SW et al.. Urinary mycoestrogens and gestational weight gain in the UPSIDE pregnancy cohort. Environ Health. 2024;23 (1):103. doi: 10.1186/s12940-024-01141-8. PubMed PMID:39567992 PubMed Central PMC11580541
- Kinkade, CW, Brinker, A, Buckley, B, Waysack, O, Fernandez, ID, Kautz, A, Meng, Y, Shi, H, Brunner, J, Ohman-Strickland, P et al.. Sociodemographic and dietary predictors of maternal and placental mycoestrogen concentrations in a US pregnancy cohort. J Expo Sci Environ Epidemiol. 2025;35 (3):382-392. doi: 10.1038/s41370-024-00722-6. PubMed PMID:39363096 PubMed Central PMC11968447
- Taylor, R, Basaly, V, Kong, B, Yang, I, Brinker, AM, Capece, G, Bhattacharya, A, Henry, ZR, Otersen, K, Yang, Z et al.. Effects of therapeutically approved individual bile acids on the development of metabolic dysfunction-associated steatohepatitis a low bile acid mouse model. Toxicol Sci. 2024;202 (2):179-195. doi: 10.1093/toxsci/kfae110. PubMed PMID:39302723
Search PubMed