Biographical Info

Lauren Aleksunes’Lab 

Recent Publications

1. Aleksunes, LM, Gray, JP, Meshanni, J, Laskin, JD, Laskin, DL. Repurposing FDA-approved drugs to treat chemical weapon toxicities: Interactive case studies for trainees. Pharmacol Res Perspect. 2024;12 (4):e1229. doi: 10.1002/prp2.1229. PubMed PMID:38965070 PubMed Central PMC11223991
2. Wen, X, Doherty, C, Thompson, LE, Kim, C, Buckley, BS, Jaimes, EA, Joy, MS, Aleksunes, LM. Determination of unbound platinum concentrations in human plasma using ultrafiltration and precipitation methods. J Pharmacol Toxicol Methods. 2024;128 :107535. doi: 10.1016/j.vascn.2024.107535. PubMed PMID:38955285
3. Kinkade, CW, Aleksunes, LM, Brinker, A, Buckley, B, Brunner, J, Wang, C, Miller, RK, O’Connor, TG, Rivera-Núñez, Z, Barrett, ES et al.. Associations between mycoestrogen exposure and sex steroid hormone concentrations in maternal serum and cord blood in the UPSIDE pregnancy cohort. Int J Hyg Environ Health. 2024;260 :114405. doi: 10.1016/j.ijheh.2024.114405. PubMed PMID:38878407
4. Gutgarts, V, Gerardine, S, Shingarev, RA, Knezevic, A, Zabor, EC, Latcha, S, Joy, MS, Aleksunes, LM, Jaimes, EA. Evaluation of Cisplatin-Induced Acute Kidney Injury in Patients Coprescribed Serotonin Receptor Antagonists: A Retrospective Analysis. Kidney360. 2024;5 (8):1094-1100. doi: 10.34067/KID.0000000000000464. PubMed PMID:38814726 PubMed Central PMC11371355
5. Chung, E, Wen, X, Jia, X, Ciallella, HL, Aleksunes, LM, Zhu, H. Hybrid non-animal modeling: A mechanistic approach to predict chemical hepatotoxicity. J Hazard Mater. 2024;471 :134297. doi: 10.1016/j.jhazmat.2024.134297. PubMed PMID:38677119
6. Galetin, A, Brouwer, KLR, Tweedie, D, Yoshida, K, Sjöstedt, N, Aleksunes, L, Chu, X, Evers, R, Hafey, MJ, Lai, Y et al.. Membrane transporters in drug development and as determinants of precision medicine. Nat Rev Drug Discov. 2024;23 (4):255-280. doi: 10.1038/s41573-023-00877-1. PubMed PMID:38267543
7. Kozlosky, D, Doherty, C, Buckley, B, Goedken, MJ, Miller, RK, Huh, DD, Barrett, ES, Aleksunes, LM. Fetoplacental Disposition and Toxicity of Cadmium in Mice Lacking the Bcrp Transporter. Toxicol Sci. 2023;197 (2):132-46. doi: 10.1093/toxsci/kfad115. PubMed PMID:37941438 PubMed Central PMC10823776
8. Zhang, R, Walker, L, Wen, X, Doherty, C, Gorczyca, L, Buckley, B, Barrett, ES, Aleksunes, LM. Placental BCRP transporter reduces cadmium accumulation and toxicity in immortalized human trophoblasts. Reprod Toxicol. 2023;121 :108466. doi: 10.1016/j.reprotox.2023.108466. PubMed PMID:37660740 PubMed Central PMC10591833
9. Russo, DP, Aleksunes, LM, Goyak, K, Qian, H, Zhu, H. Integrating Concentration-Dependent Toxicity Data and Toxicokinetics To Inform Hepatotoxicity Response Pathways. Environ Sci Technol. 2023;57 (33):12291-12301. doi: 10.1021/acs.est.3c02792. PubMed PMID:37566783 PubMed Central PMC10448720
10. Rivera-Núñez, Z, Hansel, M, Capurro, C, Kozlosky, D, Wang, C, Doherty, CL, Buckley, B, Ohman-Strickland, P, Miller, RK, O’Connor, TG et al.. Prenatal Cadmium Exposure and Maternal Sex Steroid Hormone Concentrations across Pregnancy. Toxics. 2023;11 (7):. doi: 10.3390/toxics11070589. PubMed PMID:37505555 PubMed Central PMC10384739