Lauren Aleksunes’Lab 

Recent Publications

1. Juenke, A, Hansel, MC, Kinkade, CW, Brinker, A, Bowman, M, Smith, R, Miller, RK, Brunner, J, Buckley, B, O’Connor, TG et al.. Maternal mycoestrogen exposure in relation to timing of birth and placental corticotropin releasing hormone concentrations in a U.S. pregnancy cohort. Reprod Toxicol. 2026; :109304. doi: 10.1016/j.reprotox.2026.109304. PubMed PMID:42471151
2. Cary, CM, Gadsden, NN, Zhou, P, Joseph, LB, Nguyen, C, Polunas, M, Goedken, MJ, Aleksunes, LM, Stapleton, PA. Micro and nanoplastic inhalation during gestation disrupts placentation in the Sprague-Dawley rat. Res Sq. 2026; :. doi: 10.21203/rs.3.rs-9861614/v1. PubMed PMID:42370262 PubMed Central PMC13308420
3. Rivera-Núñez, Z, Kinkade, CW, Juenke, A, Hansel, M, Heltberg, D, Sharada, A, Anthony, S, Brinker, A, Fields, J, Rosen, T et al.. Diet and mycoestrogen exposure in a pregnancy cohort: the Jersey Babies pilot study. J Expo Sci Environ Epidemiol. 2026; :. doi: 10.1038/s41370-026-00940-0. PubMed PMID:42362911
4. Asby, S, Wen, X, Goedken, M, Ames, B, Shams, S, Thompson, LE, Lanis, J, Kostka-Newman, Z, Larsen, K, Tilden, S et al.. Nephrotoxicity of Immune Checkpoint Inhibitors in Mice with a Human Immune System. bioRxiv. 2026; :. doi: 10.64898/2026.05.07.723340. PubMed PMID:42182101 PubMed Central PMC13192905
5. Campbell, MJ, Patel, M, Jiang, C, Wen, X, Xiao, S, Aleksunes, LM. Transporter-Mediated Uptake of Microcystin-LR in Human Trophoblasts: Regulation By Oxygen Concentration and Cell Fusion. bioRxiv. 2026; :. doi: 10.64898/2026.03.22.713491. PubMed PMID:41929031 PubMed Central PMC13041809
6. Jia, X, Wang, T, Russo, DP, Aleksunes, LM, Xiao, S, Zhu, H. vToxiNet: a biologically constrained deep learning framework for interpretable prediction of drug-induced hepatotoxicity. bioRxiv. 2026; :. doi: 10.64898/2026.02.26.708259. PubMed PMID:41846970 PubMed Central PMC12991077
7. Chung, E, Russo, DP, Aleksunes, LM, Warner, GR, Zhu, H. Hierarchical Mechanistic Modeling of Complex Toxicity Endpoints from Public Concentration-Response Data. Environ Sci Technol. 2026;60 (3):2539-2555. doi: 10.1021/acs.est.5c09326. PubMed PMID:41528243 PubMed Central PMC12854766
8. Basaly, V, Henry, ZR, Taylor, RE, Kong, B, Yang, I, Brinker, A, Yang, Z, Zhou, P, Joseph, LB, Aleksunes, L et al.. Mutation of PXR phosphorylation motif at Ser347 disrupts lipid and bile acid homeostasis in diet-induced metabolic dysfunction-associated steatohepatitis in mice. Drug Metab Dispos. 2026;54 (2):100222. doi: 10.1016/j.dmd.2025.100222. PubMed PMID:41520575 PubMed Central PMC12975368
9. Daood, NJ, Carey, SR, Chung, E, Wang, T, Kreutz, A, Girireddy, M, Chakravarti, S, Kleinstreuer, NC, Tiley, JB, Aleksunes, LM et al.. Machine Learning Modeling for ABC Transporter Efflux and Inhibition: Data Curation, Model Development, and New Compound Interaction Predictions. Mol Pharm. 2025;22 (11):7022-7035. doi: 10.1021/acs.molpharmaceut.5c01065. PubMed PMID:41115055 PubMed Central PMC12587445
10. Nguyen, DQ, Hyman, S, Medley, E, Bozack, AK, Kahn, LG, Kannan, K, Guitierrez, A, Aleksunes, LM, Rivera-Núñez, Z, Cowell, W et al.. Maternal organophosphate pesticide exposure in relation to birthweight: Modification by placenta transporter genotype. Placenta. 2025;172 :40-43. doi: 10.1016/j.placenta.2025.10.011. PubMed PMID:41109040 PubMed Central PMC12822829