Dr. Renping Zhou, Ph.D.

Professor Rutgers University, Ernest Mario School of PharmacyEOHSI – Toxicology
Susan Lehman Cullman Laboratory for Cancer Research Office; 217 – Lab: LCR 221 & 223 160 Frelinghuysen Road Piscataway NJ 08854 Work Phone: 848-445-7246 Work Fax: 732-445-0687 Work Phone: Lab: 848-445-7245
Photo of Dr. Renping Zhou Ph.D.

Biographical Info

Research Areas

The Zhou laboratory is interested in the mechanisms mediating cell-cell communication and their roles in normal development, physiology, and diseases. Specifically the Zhou laboratory is investigating the functions of a large family of tyrosine kinase receptors, the Ephs, and their ligands, the ephrins, in neural circuit formation, eye development, and behavior regulations including motor activity, circadian rhythm, and aggression. The Zhou laboratory employs both in vitro and in vivo techniques, including neuron cultures, transgenic and knockout mice, as well as behavior assays.

Research Highlights

Demonstration of a repulsive function of ephrins in axon guidance

Discovering signal transduction pathways mediating ephrin-induced growth cone guidance

Establishing a novel cataract mouse model

Elucidating regulation of cell-cell adhesion by ephrins

Scholarly Activities

Member of editorial board: Neuroscience Bulletin; Cell & Bioscience

Membership in: AAAS, Society of Neuroscice, ARVO

Recent Publications

  1. Varlı, M, Kim, E, Oh, S, Pulat, S, Zhou, R, Gamage, CDB, Gökalsın, B, Sesal, NC, Kim, KK, Paik, MJ et al.. Chrysophanol inhibits of colorectal cancer cell motility and energy metabolism by targeting the KITENIN/ErbB4 oncogenic complex. Cancer Cell Int. 2024;24 (1):253. doi: 10.1186/s12935-024-03434-x. PubMed PMID:39030594
  2. Lin, B, Zhou, Y, Huang, Z, Ma, M, Qi, M, Jiang, Z, Li, G, Xu, Y, Yan, J, Wang, D et al.. GPR34 senses demyelination to promote neuroinflammation and pathologies. Cell Mol Immunol. 2024; :. doi: 10.1038/s41423-024-01204-3. PubMed PMID:39030423
  3. Huang, J, Qasim, M, Zhou, R, Han, X, Ansari, MJ, Almoallim, HS, Alkherb, WAH, Wang, L. Role of chitinase expression in the virulence of Lecanicillium lecanii against citrus black aphid (Toxoptera aurantii). Int J Biol Macromol. 2024; :133970. doi: 10.1016/j.ijbiomac.2024.133970. PubMed PMID:39029816
  4. Liu, Y, Yu, Y, Wu, B, Qian, J, Mu, H, Gu, L, Zhou, R, Zhang, H, Wu, H, Bu, Y et al.. A comprehensive prediction system for silkworm acute toxicity assessment of environmental and in-silico pesticides. Ecotoxicol Environ Saf. 2024;282 :116759. doi: 10.1016/j.ecoenv.2024.116759. PubMed PMID:39029220
  5. Zhou, R, Liu, Y, Li, M, Cao, J, Cheng, J, Wei, D, Li, B, Wang, Y, Jia, D, Jiang, B et al.. Electrical Responsive Coating with a Multilayered TiO2-SnO2-RuO2 Heterostructure on Ti for Controlling Antibacterial Ability and Improving Osseointegration. ACS Appl Mater Interfaces. 2024; :. doi: 10.1021/acsami.4c07114. PubMed PMID:39028896
  6. Duan, J, Li, P, Shao, A, Hao, X, Zhou, R, Bi, C, Liu, X, Li, W, Zhu, H, Chen, G et al.. PPCRKB: a risk factor knowledge base of postoperative pulmonary complications. Database (Oxford). 2024;2024 :. doi: 10.1093/database/baae054. PubMed PMID:39028753
  7. Ruan, T, Zhou, R, Yang, Y, Guo, J, Jiang, C, Wang, X, Shen, G, Dai, S, Chen, S, Shen, Y et al.. Deficiency of IQCH causes male infertility in humans and mice. Elife. 2024;12 :. doi: 10.7554/eLife.88905. PubMed PMID:39028117 PubMed Central PMC11259432
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Categories: Faculty, Toxicology, Member, Tox Member

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