Phoebe Stapleton , Ph.D., A.T.C.

Associate Professor Rutgers UniversityEOHSI- Department of Pharmacology and Toxicology – Ernest Mario School of Pharmacy
Work Phone: 848-445-0142 -Office Work Phone: 848-445-0113 – Lab
Photo of Phoebe Stapleton Ph.D., A.T.C.

Biography

Dr. Stapleton is an Associate Professor within the Department of Pharmacology and Toxicology of the Ernest Mario School of Pharmacy at Rutgers University. She currently serves as the Division Director for Environmental and Population Health Biosciences branch of EOHSI. Dr. Stapleton also serves within the Joint Graduate Program in Toxicology.
She received her B.S. in Biology and Athletic Training from State University of New York (SUNY) College at Cortland, a M.S.Ed. in Kinesiology from Southern Illinois University at Edwardsville, and a Ph.D. in Exercise Physiology from West Virginia University with a focus on microvascular physiology. She completed her postdoctoral training in inhalation nanotoxicology within the Department of Physiology and Pharmacology at West Virginia University.

Research Areas

The microcirculation branch of the cardiovascular system encompasses the arterioles, capillaries, and venules within an organ or tissue of interest. These highly active vessels serve to maintain homeostasis by regulating blood flow and tissue perfusion, thus providing nutrients and removing waste. Central to proper reactivity is the health and function of the endothelium, a single cell layer lining the vasculature. The Stapleton laboratory investigates the microvascular perturbations associated with normal physiological challenges (exercise or pregnancy), disease, and exposures to environmental and/or occupational xenobiotics.
Our overarching research question is: how do particles inhaled during pregnancy affect the pregnant mother, fetal development, and offspring health with a focus on cardiovascular physiology. Within this umbrella, we have assessed exposure to micro- and nanoplastic particles and utilized engineered nanomaterials as a surrogate for ultrafine particulate matter with a keen focus on particle translocation, deposition, and cardiovascular perturbation. Our laboratory was previously supported by the Herbert W. Hoover Foundation and an NIEHS Outstanding New Environmental Scientist Award (ONES; NIH R01 ES031285). Our laboratory is currently supported by R01 ES036575.

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Research Highlights
 
Awards/Recognition
  • Ms. Chelsea Cary awarded the Rutgers School of Graduate Studies Aaron Shatkin Graduate Award (2023)
  • Ms. Talia Seymore was a finalist for the Trophoblast Research New Investigator Award, International Federation of Placental Association (IFPA) (2023)
  • Ms. Chelsea Cary was awarded a Kirschstein-NRSA (F31-ES035256) pre-doctoral fellowship from NIEHS (2023)
  • Laboratory publication, Maternal, placental, and fetal distribution of titanium after repeated titanium dioxide nanoparticle inhalation through pregnancy identified as top 1% of NIEHS papers published in 2022
  • Mr. Andrés D. Rivera Ruiz was awarded the SOT Undergraduate Diversity Award in 2021 for his work as an 2020 Virtual SURF trainee.
In the News

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