Lauren Aleksunes’Lab 

Recent Publications

1. Thompson, LE, Ghimire, A, Wen, X, Kim, C, Choza, J, Doherty, CL, Buckley, BT, Bowles, DW, O’Bryant, CL, Pfister, DG et al.. A Pharmacokinetic/Toxicodynamic Model of Cisplatin Nephrotoxicity Using the Kidney Injury Molecule-1 Biomarker. J Pharmacol Clin Toxicol. 2024;12 (1):. doi: 10.47739/pharmacology1184. PubMed PMID:39726772 PubMed Central PMC11671133
2. Thompson, LE, Ghimire, A, Wen, X, Kim, C, Doherty, CL, Buckley, BT, Bowles, DW, O’Bryant, CL, Jaimes, EA, Aleksunes, LM et al.. Population Pharmacokinetic Model of Platinum Disposition in Cancer Patients Receiving Cisplatin and Randomized to 5-HT₃ Antagonist Antiemetic Drugs. J Clin Pharmacol. 2024; :. doi: 10.1002/jcph.6177. PubMed PMID:39711135
3. Toth, E, Li, H, Frost, K, Sample, P, Jilek, J, Greenfield, S, You, D, Kozlosky, D, Goedken, M, Paine, MF et al.. Nonalcoholic steatohepatitis increases plasma retention of sorafenib-glucuronide in a mouse model by altering hepatocyte hopping. Acta Pharm Sin B. 2024;14 (11):4874-4882. doi: 10.1016/j.apsb.2024.09.004. PubMed PMID:39664440 PubMed Central PMC11628858
4. Kinkade, CW, Rivera-Núñez, Z, Brinker, A, Buckley, B, Waysack, O, Kautz, A, Meng, Y, Ohman Strickland, P, Block, R, Groth, SW et al.. Urinary mycoestrogens and gestational weight gain in the UPSIDE pregnancy cohort. Environ Health. 2024;23 (1):103. doi: 10.1186/s12940-024-01141-8. PubMed PMID:39567992 PubMed Central PMC11580541
5. Kinkade, CW, Brinker, A, Buckley, B, Waysack, O, Fernandez, ID, Kautz, A, Meng, Y, Shi, H, Brunner, J, Ohman-Strickland, P et al.. Sociodemographic and dietary predictors of maternal and placental mycoestrogen concentrations in a US pregnancy cohort. J Expo Sci Environ Epidemiol. 2024; :. doi: 10.1038/s41370-024-00722-6. PubMed PMID:39363096
6. Taylor, R, Basaly, V, Kong, B, Yang, I, Brinker, AM, Capece, G, Bhattacharya, A, Henry, ZR, Otersen, K, Yang, Z et al.. Effects of therapeutically approved individual bile acids on the development of metabolic dysfunction-associated steatohepatitis a low bile acid mouse model. Toxicol Sci. 2024;202 (2):179-195. doi: 10.1093/toxsci/kfae110. PubMed PMID:39302723
7. Aleksunes, LM, Gray, JP, Meshanni, J, Laskin, JD, Laskin, DL. Repurposing FDA-approved drugs to treat chemical weapon toxicities: Interactive case studies for trainees. Pharmacol Res Perspect. 2024;12 (4):e1229. doi: 10.1002/prp2.1229. PubMed PMID:38965070 PubMed Central PMC11223991
8. Wen, X, Doherty, C, Thompson, LE, Kim, C, Buckley, BS, Jaimes, EA, Joy, MS, Aleksunes, LM. Determination of unbound platinum concentrations in human plasma using ultrafiltration and precipitation methods. J Pharmacol Toxicol Methods. 2024;128 :107535. doi: 10.1016/j.vascn.2024.107535. PubMed PMID:38955285 PubMed Central PMC11551886
9. Kinkade, CW, Aleksunes, LM, Brinker, A, Buckley, B, Brunner, J, Wang, C, Miller, RK, O’Connor, TG, Rivera-Núñez, Z, Barrett, ES et al.. Associations between mycoestrogen exposure and sex steroid hormone concentrations in maternal serum and cord blood in the UPSIDE pregnancy cohort. Int J Hyg Environ Health. 2024;260 :114405. doi: 10.1016/j.ijheh.2024.114405. PubMed PMID:38878407 PubMed Central PMC11441442
10. Gutgarts, V, Gerardine, S, Shingarev, RA, Knezevic, A, Zabor, EC, Latcha, S, Joy, MS, Aleksunes, LM, Jaimes, EA. Evaluation of Cisplatin-Induced Acute Kidney Injury in Patients Coprescribed Serotonin Receptor Antagonists: A Retrospective Analysis. Kidney360. 2024;5 (8):1094-1100. doi: 10.34067/KID.0000000000000464. PubMed PMID:38814726 PubMed Central PMC11371355