Controlled human exposure health effects studies, incorporating chemical exposures and psychological stress to model realistic environmental exposures.
Epidemiologic investigations of toxic encephalopathy among workers chronically exposed to solvents and lead with a focus on integrating neuropsychological testing, exposure assessment, and functional imaging.
Translational research to examine whether alteration in HPA axis function among lead exposed animals translates to humans chronically exposed to lead
International studies based in Thailand to investigate the cognitive and behavioral effects of pesticide exposure in a birth cohort
Research Highlights
Discovered a negative dose response relationship between lifetime solvent exposure and functional imaging activation patterns during performance of a working memory task.
Demonstrated neurobehavioral performance deficits among workers chronically exposed to solvents
Validated a lifetime solvent exposure index with neurobehavioral performance among workers chronically exposed to solvent mixtures
Current blood and bone lead alters hypothalamic pituitary adrenal axis function among workers with lifetime exposure
Developing behavioral research capacity among public health students at Chulalongkorn University, Bangkok, Thailand.
Scholarly Activities
Member of the Joint Graduate Program in Toxicology, Rutgers University
NIH Fogarty International Center Grant reviewer
Co-Chair for the New Jersey Alliance for Clinical and Translational Science Scientific Review Board
New Jersey Kids Study Co-Chair for neurodevelopmental assessment
EOHSI representative for the RBHS Mentor Committee
Chair for the EOHSI Faculty Search Committee
Recent Publications
Click here for additiional publications by Dr. Fiedler.
Baumert, BO, Fiedler, N, Prapamontol, T, Suttiwan, P, Naksen, W, Panuwet, P, Sittiwang, S, Dokjunyam, C, Smarr, MM, Marsit, CJ et al.. Investigation of Prenatal Pesticide Exposure and Neurodevelopmental Deficits in Northern Thailand: Protocol for a Longitudinal Birth Cohort Study. JMIR Res Protoc. 2022;11 (2):e31696. doi: 10.2196/31696. PubMed PMID:35129451 PubMed Central PMC8861866
Baumert, BO, Fiedler, N, Prapamontol, T, Naksen, W, Panuwet, P, Hongsibsong, S, Wongkampaun, A, Thongjan, N, Lee, G, Sittiwang, S et al.. Urinary Concentrations of Dialkylphosphate Metabolites of Organophosphate pesticides in the Study of Asian Women and their Offspring’s Development and Environmental Exposures (SAWASDEE). Environ Int. 2022;158 :106884. doi: 10.1016/j.envint.2021.106884. PubMed PMID:34583095 PubMed Central PMC8688265
Castle, M, Fiedler, N, Pop, LC, Schneider, SJ, Schlussel, Y, Sukumar, D, Hao, L, Shapses, SA. Three Doses of Vitamin D and Cognitive Outcomes in Older Women: A Double-Blind Randomized Controlled Trial. J Gerontol A Biol Sci Med Sci. 2020;75 (5):835-842. doi: 10.1093/gerona/glz041. PubMed PMID:30951148 PubMed Central PMC7164532
Fiedler, N, Weisel, C, Nwankwo, C, Kipen, H, Lange, G, Ohman-Strickland, P, Laumbach, R. Chronic Exposure to Solvents Among Construction Painters: Reductions in Exposure and Neurobehavioral Health Effects. J Occup Environ Med. 2018;60 (12):e663-e670. doi: 10.1097/JOM.0000000000001470. PubMed PMID:30308619 PubMed Central PMC6289817
Fiedler, N, Rohitrattana, J, Siriwong, W, Suttiwan, P, Ohman Strickland, P, Ryan, PB, Rohlman, DS, Panuwet, P, Barr, DB, Robson, MG et al.. Neurobehavioral effects of exposure to organophosphates and pyrethroid pesticides among Thai children. Neurotoxicology. 2015;48 :90-9. doi: 10.1016/j.neuro.2015.02.003. PubMed PMID:25721160 PubMed Central PMC4442703
Rohitrattana, J, Siriwong, W, Robson, M, Panuwet, P, Barr, DB, Fiedler, N. Pyrethroid insecticide exposure in school-aged children living in rice and aquacultural farming regions of Thailand. Risk Manag Healthc Policy. 2014;7 :211-7. doi: 10.2147/RMHP.S67208. PubMed PMID:25395873 PubMed Central PMC4227621
Ruggiero, JS, Redeker, NS, Fiedler, N, Avi-Itzhak, T, Fischetti, N. Sleep and psychomotor vigilance in female shiftworkers. Biol Res Nurs. 2012;14 (3):225-35. doi: 10.1177/1099800411408413. PubMed PMID:21708893
Laumbach, RJ, Kipen, HM, Kelly-McNeil, K, Zhang, J, Zhang, L, Lioy, PJ, Ohman-Strickland, P, Gong, J, Kusnecov, A, Fiedler, N et al.. Sickness response symptoms among healthy volunteers after controlled exposures to diesel exhaust and psychological stress. Environ Health Perspect. 2011;119 (7):945-50. doi: 10.1289/ehp.1002631. PubMed PMID:21330231 PubMed Central PMC3223003
Laumbach, R, Tong, J, Zhang, L, Ohman-Strickland, P, Stern, A, Fiedler, N, Kipen, H, Kelly-McNeil, K, Lioy, P, Zhang, J et al.. Quantification of 1-aminopyrene in human urine after a controlled exposure to diesel exhaust. J Environ Monit. 2009;11 (1):153-9. doi: 10.1039/b810039j. PubMed PMID:19137151 PubMed Central PMC4049318
Osinubi, OY, Gandhi, SK, Ohman-Strickland, P, Boglarsky, C, Fiedler, N, Kipen, H, Robson, M. Organizational factors and office workers’ health after the World Trade Center terrorist attacks: long-term physical symptoms, psychological distress, and work productivity. J Occup Environ Med. 2008;50 (2):112-25. doi: 10.1097/JOM.0b013e31815e92bd. PubMed PMID:18301168