Renping Zhou Ph.D. » EOHSI Directory

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Renping Zhou Ph.D.

Professor Rutgers University, Ernest Mario School of PharmacyEOHSI – Toxicology
Address William Levine Hall Room 217 160 Frelinghuysen Road Piscataway NJ 08854 Phone: 848-445-7246 Fax: 732-445-0687
Photo of Renping Zhou Ph.D.

Biographical Info

Research Areas

The Zhou laboratory is interested in the mechanisms mediating cell-cell communication and their roles in normal development, physiology, and diseases. Specifically the Zhou laboratory is investigating the functions of a large family of tyrosine kinase receptors, the Ephs, and their ligands, the ephrins, in neural circuit formation, eye development, and behavior regulations including motor activity, circadian rhythm, and aggression. The Zhou laboratory employs both in vitro and in vivo techniques, including neuron cultures, transgenic and knockout mice, as well as behavior assays.

Research Highlights

Demonstration of a repulsive function of ephrins in axon guidance

Discovering signal transduction pathways mediating ephrin-induced growth cone guidance

Establishing a novel cataract mouse model

Elucidating regulation of cell-cell adhesion by ephrins

Scholarly Activities

Member of editorial board: Neuroscience Bulletin; Cell & Bioscience

Membership in: AAAS, Society of Neuroscice, ARVO

Recent Publications

  1. Yu, Q, Hui, R, Park, J, Huang, Y, Kusnecov, AW, Dreyfus, CF, Zhou, R. Strain differences in cuprizone induced demyelination. Cell Biosci. 2017;7 :59. doi: 10.1186/s13578-017-0181-3. PubMed PMID:29142736 PubMed Central PMC5670722
  2. Sheleg, M, Yochum, CL, Richardson, JR, Wagner, GC, Zhou, R. Corrigendum to "Ephrin-A5 regulates inter-male aggression in mice" [Behav. Brain Res. 286 (June) (2015) 300-307]. Behav. Brain Res. 2017;335 :223. doi: 10.1016/j.bbr.2017.08.019. PubMed PMID:28827072
  3. Das, G, Yu, Q, Hui, R, Reuhl, K, Gale, NW, Zhou, R. EphA5 and EphA6: regulation of neuronal and spine morphology. Cell Biosci. 2016;6 :48. doi: 10.1186/s13578-016-0115-5. PubMed PMID:27489614 PubMed Central PMC4971699
  4. Buensuceso, AV, Son, AI, Zhou, R, Paquet, M, Withers, BM, Deroo, BJ. Ephrin-A5 Is Required for Optimal Fertility and a Complete Ovulatory Response to Gonadotropins in the Female Mouse. Endocrinology. 2016;157 (2):942-55. doi: 10.1210/en.2015-1216. PubMed PMID:26672804
  5. Biswas, S, Son, A, Yu, Q, Zhou, R, Lo, WK. Breakdown of interlocking domains may contribute to formation of membranous globules and lens opacity in ephrin-A5(-/-) mice. Exp. Eye Res. 2016;145 :130-139. doi: 10.1016/j.exer.2015.11.017. PubMed PMID:26643403 PubMed Central PMC4842153
  6. Sheleg, M, Yochum, CL, Richardson, JR, Wagner, GC, Zhou, R. Ephrin-A5 regulates inter-male aggression in mice. Behav. Brain Res. 2015;286 :300-7. doi: 10.1016/j.bbr.2015.03.001. PubMed PMID:25746458 PubMed Central PMC4390541
  7. Son, AI, Sheleg, M, Cooper, MA, Sun, Y, Kleiman, NJ, Zhou, R. Formation of persistent hyperplastic primary vitreous in ephrin-A5-/- mice. Invest. Ophthalmol. Vis. Sci. 2014;55 (3):1594-606. doi: 10.1167/iovs.13-12706. PubMed PMID:24550361 PubMed Central PMC4586972
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Categories: Faculty, Toxicology

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