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Renping Zhou Ph.D.

Professor Rutgers University, Ernest Mario School of PharmacyEOHSI – Toxicology
Work William Levine Hall Room 217 160 Frelinghuysen Road Piscataway NJ 08854 Work Phone: 848-445-7246 Work Fax: 732-445-0687
Photo of Renping Zhou Ph.D.

Biographical Info

Research Areas

The Zhou laboratory is interested in the mechanisms mediating cell-cell communication and their roles in normal development, physiology, and diseases. Specifically the Zhou laboratory is investigating the functions of a large family of tyrosine kinase receptors, the Ephs, and their ligands, the ephrins, in neural circuit formation, eye development, and behavior regulations including motor activity, circadian rhythm, and aggression. The Zhou laboratory employs both in vitro and in vivo techniques, including neuron cultures, transgenic and knockout mice, as well as behavior assays.

Research Highlights

Demonstration of a repulsive function of ephrins in axon guidance

Discovering signal transduction pathways mediating ephrin-induced growth cone guidance

Establishing a novel cataract mouse model

Elucidating regulation of cell-cell adhesion by ephrins

Scholarly Activities

Member of editorial board: Neuroscience Bulletin; Cell & Bioscience

Membership in: AAAS, Society of Neuroscice, ARVO

Recent Publications

  1. Bao, L, Zhou, R, Wu, Y, Wang, J, Shen, M, Lu, F, Wang, H, Chen, Q. Unique changes in the retinal microvasculature reveal subclinical retinal impairment in patients with systemic lupus erythematosus. Microvasc. Res. 2019; :103957. doi: 10.1016/j.mvr.2019.103957. PubMed PMID:31733303
  2. Zhou, R, Qin, Y, Padoan, A, Sciacovelli, L, Aita, A, Wang, Q, Plebani, M. Different approaches for estimating measurement uncertainty: an effective tool for improving interpretation of results. Clin. Chim. Acta. 2019; :. doi: 10.1016/j.cca.2019.11.011. PubMed PMID:31733194
  3. Qiao, L, Lv, T, Xu, Y, Zhang, M, Zhang, J, Wang, T, Zhou, R, Wang, Q, Xu, H. Generation of flat wideband chaos based on mutual injection of semiconductor lasers. Opt Lett. 2019;44 (22):5394-5397. doi: 10.1364/OL.44.005394. PubMed PMID:31730066
  4. Zhan, X, Yang, M, Zhou, R, Wei, X, Chen, Y, Chen, Q. Triglyceride to high-density lipoprotein cholesterol ratio is associated with increased mortality in older patients on peritoneal dialysis. Lipids Health Dis. 2019;18 (1):199. doi: 10.1186/s12944-019-1147-8. PubMed PMID:31729985
  5. Harrison, SA, Bashir, MR, Guy, CD, Zhou, R, Moylan, CA, Frias, JP, Alkhouri, N, Bansal, MB, Baum, S, Neuschwander-Tetri, BA et al.. Resmetirom (MGL-3196) for the treatment of non-alcoholic steatohepatitis: a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial. Lancet. 2019; :. doi: 10.1016/S0140-6736(19)32517-6. PubMed PMID:31727409
  6. Zhou, R, Mo, W, Wang, S, Zhou, W, Chen, X, Pan, S. miR-141-3p and TRAF5 Network Contributes to the Progression of T-Cell Acute Lymphoblastic Leukemia. Cell Transplant. 2019; :963689719887370. doi: 10.1177/0963689719887370. PubMed PMID:31722554
  7. Tian, L, You, HZ, Wu, H, Wei, Y, Zheng, M, He, L, Liu, JY, Guo, SZ, Zhao, Y, Zhou, RL et al.. iTRAQ-based quantitative proteomic analysis provides insight for molecular mechanism of neuroticism. Clin Proteomics. 2019;16 :38. doi: 10.1186/s12014-019-9259-8. PubMed PMID:31719821 PubMed Central PMC6839193
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Categories: Faculty, Toxicology
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