< Dr. Renping Zhou Ph.D. EOHSI Directory | EOHSI


Dr. Renping Zhou, Ph.D.

Professor Rutgers University, Ernest Mario School of PharmacyEOHSI – Toxicology
Work Susan Lehman Cullman Laboratory for Cancer Research Office; 217 – Lab: LCR 221 & 223 160 Frelinghuysen Road Piscataway NJ 08854 Work Phone: 848-445-7246 Work Fax: 732-445-0687 Work Phone: Lab: 848-445-7245
Photo of Dr. Renping Zhou Ph.D.

Biographical Info

Research Areas

The Zhou laboratory is interested in the mechanisms mediating cell-cell communication and their roles in normal development, physiology, and diseases. Specifically the Zhou laboratory is investigating the functions of a large family of tyrosine kinase receptors, the Ephs, and their ligands, the ephrins, in neural circuit formation, eye development, and behavior regulations including motor activity, circadian rhythm, and aggression. The Zhou laboratory employs both in vitro and in vivo techniques, including neuron cultures, transgenic and knockout mice, as well as behavior assays.

Research Highlights

Demonstration of a repulsive function of ephrins in axon guidance

Discovering signal transduction pathways mediating ephrin-induced growth cone guidance

Establishing a novel cataract mouse model

Elucidating regulation of cell-cell adhesion by ephrins

Scholarly Activities

Member of editorial board: Neuroscience Bulletin; Cell & Bioscience

Membership in: AAAS, Society of Neuroscice, ARVO

Recent Publications

  1. Sheng, Z, Xu, J, Li, F, Yuan, Y, Peng, X, Chen, S, Zhou, R, Huang, W. The RING-domain E3 ubiquitin ligase RNF146 promotes cardiac hypertrophy by suppressing the LKB1/AMPK signaling pathway. Exp Cell Res. 2021; :112954. doi: 10.1016/j.yexcr.2021.112954. PubMed PMID:34856161
  2. Liao, X, Li, H, Khan, A, Zhao, Y, Raza, MA, Zhou, B, Zhou, R, Hou, W, Tang, X. Nucleo-cytoplasmic interactions affect the 5' terminal transcription of mitochondrial genes between the isonuclear CMS line UG93A and its maintainer line UG93B of kenaf (Hibiscus cannabinus). Dev Genes Evol. 2021; :. doi: 10.1007/s00427-021-00682-z. PubMed PMID:34854979
  3. Wang, YH, Zheng, S, Yang, WM, Zhou, RY, He, QF, Radjenovic, P, Dong, JC, Li, S, Zheng, J, Yang, ZL et al.. In situ Raman spectroscopy reveals the structure and dissociation of interfacial water. Nature. 2021;600 (7887):81-85. doi: 10.1038/s41586-021-04068-z. PubMed PMID:34853456
  4. Jiang, W, Zhao, W, Ye, F, Huang, S, Wu, Y, Chen, H, Zhou, R, Fu, G. SNHG12 regulates biological behaviors of ox-LDL-induced HA-VSMCs through upregulation of SPRY2 and NUB1. Atherosclerosis. 2021;340 :1-11. doi: 10.1016/j.atherosclerosis.2021.11.006. PubMed PMID:34847450
  5. Liu, J, Liu, S, Zheng, K, Tang, M, Gu, L, Young, J, Wang, Z, Qiu, Y, Dong, J, Gu, S et al.. Chromosome-level genome assembly of the Chinese three-keeled pond turtle (Mauremys reevesii) provides insights into freshwater adaptation. Mol Ecol Resour. 2021; :. doi: 10.1111/1755-0998.13563. PubMed PMID:34845835
  6. Zheng, X, Zhang, D, Xu, M, Zeng, W, Zhou, R, Zhang, Y, Tang, C, Chen, L, Chen, L, Lin, JW et al.. Short-read and long-read RNA sequencing of mouse hematopoietic stem cells at bulk and single-cell levels. Sci Data. 2021;8 (1):309. doi: 10.1038/s41597-021-01078-4. PubMed PMID:34845251
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Categories: Faculty, Toxicology, Member, Tox Member
Updated 6 months ago.