EOHSI- Deputy Director, Professor – Rutgers School of Public Health
Rutgers University – School of Public HealthEOHSI – Clinical Research and Occupational Medicine
Work Phone: 848-445-6081work
Work Fax: 732-445-0130workfax
Work Email: nfiedler@eohsi.rutgers.eduINTERNET
Biography
Research Areas
- Controlled human exposure health effects studies, incorporating chemical exposures and psychological stress to model realistic environmental exposures.
- Epidemiologic investigations of toxic encephalopathy among workers chronically exposed to solvents and lead with a focus on integrating neuropsychological testing, exposure assessment, and functional imaging.
- Translational research to examine whether alteration in HPA axis function among lead exposed animals translates to humans chronically exposed to lead
- International studies based in Thailand to investigate the cognitive and behavioral effects of pesticide exposure in a birth cohort
Research Highlights
- Discovered a negative dose response relationship between lifetime solvent exposure and functional imaging activation patterns during performance of a working memory task.
- Demonstrated neurobehavioral performance deficits among workers chronically exposed to solvents
- Validated a lifetime solvent exposure index with neurobehavioral performance among workers chronically exposed to solvent mixtures
- Current blood and bone lead alters hypothalamic pituitary adrenal axis function among workers with lifetime exposure
- Developing behavioral research capacity among public health students at Chulalongkorn University, Bangkok, Thailand.
Scholarly Activities
- Member of the Joint Graduate Program in Toxicology, Rutgers University
- NIH Fogarty International Center Grant reviewer
- Co-Chair for the New Jersey Alliance for Clinical and Translational Science Scientific Review Board
- New Jersey Kids Study Co-Chair for neurodevelopmental assessment
- EOHSI representative for the RBHS Mentor Committee
- Chair for the EOHSI Faculty Search Committee
Recent Publications
Click here for additiional publications by Dr. Fiedler.
- Dang, T, Sehgal, N, Barr, DB, Panuwet, P, Liang, D, Smarr, M, Naksen, W, Fiedler, N, Promkam, N, Prapamontol, T et al.. Association of prenatal chlorpyrifos exposure with sexually dimorphic differences in anogenital distance among Thai farmworker children. Environ Res. 2024;248 :118325. doi: 10.1016/j.envres.2024.118325. PubMed PMID:38286251
- Nimmapirat, P, Fiedler, N, Suttiwan, P, Sullivan, MW, Ohman-Strickland, P, Panuwet, P, Barr, DB, Prapamontol, T, Naksen, W, SAWASDEE birth cohort investigative team et al.. Predictors of executive function among 2 year olds from a Thai birth cohort. Infant Behav Dev. 2024;74 :101916. doi: 10.1016/j.infbeh.2023.101916. PubMed PMID:38096613 PubMed Central PMC10947867
- Rattanawitoon, T, Siriwong, W, Shendell, D, Fiedler, N, Robson, MG. An Evaluation of a Pesticide Training Program to Reduce Pesticide Exposure and Enhance Safety among Female Farmworkers in Nan, Thailand. Int J Environ Res Public Health. 2023;20 (17):. doi: 10.3390/ijerph20176635. PubMed PMID:37681775 PubMed Central PMC10487852
- Li, Q, Lesseur, C, Srirangam, P, Kaur, K, Hermetz, K, Caudle, WM, Fiedler, N, Panuwet, P, Prapamontol, T, Naksen, W et al.. Associations between prenatal organophosphate pesticide exposure and placental gene networks. Environ Res. 2023;224 :115490. doi: 10.1016/j.envres.2023.115490. PubMed PMID:36828252 PubMed Central PMC10054353
- Liang, D, Batross, J, Fiedler, N, Prapamontol, T, Suttiwan, P, Panuwet, P, Naksen, W, Baumert, BO, Yakimavets, V, Tan, Y et al.. Metabolome-wide association study of the relationship between chlorpyrifos exposure and first trimester serum metabolite levels in pregnant Thai farmworkers. Environ Res. 2022;215 (Pt 2):114319. doi: 10.1016/j.envres.2022.114319. PubMed PMID:36108722 PubMed Central PMC9909724
- Baumert, BO, Fiedler, N, Prapamontol, T, Suttiwan, P, Naksen, W, Panuwet, P, Sittiwang, S, Dokjunyam, C, Smarr, MM, Marsit, CJ et al.. Investigation of Prenatal Pesticide Exposure and Neurodevelopmental Deficits in Northern Thailand: Protocol for a Longitudinal Birth Cohort Study. JMIR Res Protoc. 2022;11 (2):e31696. doi: 10.2196/31696. PubMed PMID:35129451 PubMed Central PMC8861866
- Sittiwang, S, Nimmapirat, P, Suttiwan, P, Promduang, W, Chaikittipornlert, N, Wouldes, T, Prapamontol, T, Naksen, W, Promkam, N, Pingwong, S et al.. The relationship between prenatal exposure to organophosphate insecticides and neurodevelopmental integrity of infants at 5-weeks of age. Front Epidemiol. 2022;2 :. doi: 10.3389/fepid.2022.1039922. PubMed PMID:36925965 PubMed Central PMC10016628
- Baumert, BO, Fiedler, N, Prapamontol, T, Naksen, W, Panuwet, P, Hongsibsong, S, Wongkampaun, A, Thongjan, N, Lee, G, Sittiwang, S et al.. Urinary Concentrations of Dialkylphosphate Metabolites of Organophosphate pesticides in the Study of Asian Women and their Offspring’s Development and Environmental Exposures (SAWASDEE). Environ Int. 2022;158 :106884. doi: 10.1016/j.envint.2021.106884. PubMed PMID:34583095 PubMed Central PMC8688265
- Castle, M, Fiedler, N, Pop, LC, Schneider, SJ, Schlussel, Y, Sukumar, D, Hao, L, Shapses, SA. Three Doses of Vitamin D and Cognitive Outcomes in Older Women: A Double-Blind Randomized Controlled Trial. J Gerontol A Biol Sci Med Sci. 2020;75 (5):835-842. doi: 10.1093/gerona/glz041. PubMed PMID:30951148 PubMed Central PMC7164532
- Fiedler, N, Weisel, C, Nwankwo, C, Kipen, H, Lange, G, Ohman-Strickland, P, Laumbach, R. Chronic Exposure to Solvents Among Construction Painters: Reductions in Exposure and Neurobehavioral Health Effects. J Occup Environ Med. 2018;60 (12):e663-e670. doi: 10.1097/JOM.0000000000001470. PubMed PMID:30308619 PubMed Central PMC6289817
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