Biographical Info

Research Areas

• Controlled human exposure health effects studies, incorporating chemical exposures and psychological stress to model realistic environmental exposures.
• Epidemiologic investigations of toxic encephalopathy among workers chronically exposed to solvents and lead with a focus on integrating neuropsychological testing, exposure assessment, and functional imaging.
• Translational research to examine whether alteration in HPA axis function among lead exposed animals translates to humans chronically exposed to lead
• International studies based in Thailand to investigate the cognitive and behavioral effects of pesticide exposure in a birth cohort

Research Highlights

• Discovered a negative dose response relationship between lifetime solvent exposure and functional imaging activation patterns during performance of a working memory task.
• Demonstrated neurobehavioral performance deficits among workers chronically exposed to solvents
• Validated a lifetime solvent exposure index with neurobehavioral performance among workers chronically exposed to solvent mixtures
• Current blood and bone lead alters hypothalamic pituitary adrenal axis function among workers with lifetime exposure
• Developing behavioral research capacity among public health students at Chulalongkorn University, Bangkok, Thailand.

Scholarly Activities

• Member of the Joint Graduate Program in Toxicology, Rutgers University
• NIH Fogarty International Center Grant reviewer
• Co-Chair for the New Jersey Alliance for Clinical and Translational Science Scientific Review Board
• New Jersey Kids Study Co-Chair for neurodevelopmental assessment
• EOHSI representative for the RBHS Mentor Committee
• Chair for the EOHSI Faculty Search Committee

Recent Publications

Click here for additiional publications by Dr. Fiedler.

1. Li, Q, Lesseur, C, Srirangam, P, Kaur, K, Hermetz, K, Caudle, WM, Fiedler, N, Panuwet, P, Prapamontol, T, Naksen, W et al.. Associations between prenatal organophosphate pesticide exposure and placental gene networks. Environ Res. 2023;224 :115490. doi: 10.1016/j.envres.2023.115490. PubMed PMID:36828252 PubMed Central PMC10054353
2. Liang, D, Batross, J, Fiedler, N, Prapamontol, T, Suttiwan, P, Panuwet, P, Naksen, W, Baumert, BO, Yakimavets, V, Tan, Y et al.. Metabolome-wide association study of the relationship between chlorpyrifos exposure and first trimester serum metabolite levels in pregnant Thai farmworkers. Environ Res. 2022;215 (Pt 2):114319. doi: 10.1016/j.envres.2022.114319. PubMed PMID:36108722 PubMed Central PMC9909724
3. Baumert, BO, Fiedler, N, Prapamontol, T, Suttiwan, P, Naksen, W, Panuwet, P, Sittiwang, S, Dokjunyam, C, Smarr, MM, Marsit, CJ et al.. Investigation of Prenatal Pesticide Exposure and Neurodevelopmental Deficits in Northern Thailand: Protocol for a Longitudinal Birth Cohort Study. JMIR Res Protoc. 2022;11 (2):e31696. doi: 10.2196/31696. PubMed PMID:35129451 PubMed Central PMC8861866
4. Sittiwang, S, Nimmapirat, P, Suttiwan, P, Promduang, W, Chaikittipornlert, N, Wouldes, T, Prapamontol, T, Naksen, W, Promkam, N, Pingwong, S et al.. The relationship between prenatal exposure to organophosphate insecticides and neurodevelopmental integrity of infants at 5-weeks of age. Front Epidemiol. 2022;2 :. doi: 10.3389/fepid.2022.1039922. PubMed PMID:36925965 PubMed Central PMC10016628
5. Baumert, BO, Fiedler, N, Prapamontol, T, Naksen, W, Panuwet, P, Hongsibsong, S, Wongkampaun, A, Thongjan, N, Lee, G, Sittiwang, S et al.. Urinary Concentrations of Dialkylphosphate Metabolites of Organophosphate pesticides in the Study of Asian Women and their Offspring’s Development and Environmental Exposures (SAWASDEE). Environ Int. 2022;158 :106884. doi: 10.1016/j.envint.2021.106884. PubMed PMID:34583095 PubMed Central PMC8688265
6. Castle, M, Fiedler, N, Pop, LC, Schneider, SJ, Schlussel, Y, Sukumar, D, Hao, L, Shapses, SA. Three Doses of Vitamin D and Cognitive Outcomes in Older Women: A Double-Blind Randomized Controlled Trial. J Gerontol A Biol Sci Med Sci. 2020;75 (5):835-842. doi: 10.1093/gerona/glz041. PubMed PMID:30951148 PubMed Central PMC7164532
7. Fiedler, N, Weisel, C, Nwankwo, C, Kipen, H, Lange, G, Ohman-Strickland, P, Laumbach, R. Chronic Exposure to Solvents Among Construction Painters: Reductions in Exposure and Neurobehavioral Health Effects. J Occup Environ Med. 2018;60 (12):e663-e670. doi: 10.1097/JOM.0000000000001470. PubMed PMID:30308619 PubMed Central PMC6289817
8. Fiedler, N, Rohitrattana, J, Siriwong, W, Suttiwan, P, Ohman Strickland, P, Ryan, PB, Rohlman, DS, Panuwet, P, Barr, DB, Robson, MG et al.. Neurobehavioral effects of exposure to organophosphates and pyrethroid pesticides among Thai children. Neurotoxicology. 2015;48 :90-9. doi: 10.1016/j.neuro.2015.02.003. PubMed PMID:25721160 PubMed Central PMC4442703
9. Rohitrattana, J, Siriwong, W, Robson, M, Panuwet, P, Barr, DB, Fiedler, N. Pyrethroid insecticide exposure in school-aged children living in rice and aquacultural farming regions of Thailand. Risk Manag Healthc Policy. 2014;7 :211-7. doi: 10.2147/RMHP.S67208. PubMed PMID:25395873 PubMed Central PMC4227621
10. Ruggiero, JS, Redeker, NS, Fiedler, N, Avi-Itzhak, T, Fischetti, N. Sleep and psychomotor vigilance in female shiftworkers. Biol Res Nurs. 2012;14 (3):225-35. doi: 10.1177/1099800411408413. PubMed PMID:21708893