Abstract: Cancer and cardiovascular disease are influenced by the spatial context in which people live. Environmental and neighborhood socioeconomic exposures are etiologically relevant for many chronic diseases via multiple mechanistic pathways. In this talk, Charlie will discuss her work on environmental exposure assessment for epidemiology, including the use of Earth Observation technologies. Additionally, she’ll discuss her recent work with Dr Hari Iyer (Assistant Professor at Rutgers Cancer Institute of New Jersey) to model hypothetical environmental interventions to reduce cancer outcome disparities. Finally, she’ll propose the Exposome as a multi-level framework to integrate geospatial context (across the lifecourse) into investigations of mechanisms that drive cancer, cardiovascular disease, and other environmentally-susceptible chronic disease outcomes.