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Chung “CS” Yang Ph.D.

Distinguished Professor & John L. Colaizzi Endowed Chair in Pharmacy Rutgers University, Ernest Mario School of PharmacyEOHSI – Toxicology
Work William Levine Hall Room 129 160 Frelinghuysen Road Piscataway NJ 08854 Work Phone: 848-445-5360 Work Fax: 732-445-0687
Photo of Chung “CS” Yang Ph.D.

Biographical Info

Research Areas

Mechanisms of carcinogenesis and its prevention, including development of new animal models for colon ad prostate cancers as well as studies on the inhibition of carcinogenesis by tea constituents, tocopherols, and their combination with commonly used drugs. Research is being conducted in animal models, on molecular investigation with cell lines, and in humans.

Research Highlights

  • Development of animal models for colon and prostate cancers using humanized CYP1A mice and PhIP (a dietary carcinogen) to study dietary cancer prevention.
  • Elucidation of the cancer preventive activities and mechanisms of action of green tea polyphenols.
  • Demonstration of the broad cancer prevention activities of tocopherols, especially the higher activity of d-tocopherol than g-tocopherol, and the ineffectiveness of a-tocopherol.
  • Elucidation of the inhibition of the interactions between cancer cells and myeloid derived suppressor cells in vivo and in vitro by curcumin.
  • Conducting translational research on tocopherols in prostate cancer patients.

Scholarly Activities

  • Conduct research as described above.
  • Teach a course on “Diet, Nutrition and Disease Prevention in Pharmacy Practice” and lecture in the course “Molecular Biology and Pharmaceutical Biotechnology.”
  • Serve as a Leader of the Carcinogenesis and Chemoprevention Program of the Cancer Institute of New Jersey.
  • Serve on editorial board of several scientific journals and currently editing a special volume on “Tea and Health” for Pharmacological Research.

Recent Publications

  1. Yang, HY, Yang, CS. Development of a full thickness macular hole after vitrectomy for rhegmatogenous retinal detachment: a sequential study via optical coherence tomography. BMC Ophthalmol. 2018;18 (1):265. doi: 10.1186/s12886-018-0932-x. PubMed PMID:30314435
  2. Feng, S, Dai, Z, Liu, AB, Huang, J, Narsipur, N, Guo, G, Kong, B, Reuhl, K, Lu, W, Luo, Z et al.. Intake of stigmasterol and β-sitosterol alters lipid metabolism and alleviates NAFLD in mice fed a high-fat western-style diet. Biochim Biophys Acta Mol Cell Biol Lipids. 2018;1863 (10):1274-1284. doi: 10.1016/j.bbalip.2018.08.004. PubMed PMID:30305244
  3. Jividen, K, Kedzierska, KZ, Yang, CS, Szlachta, K, Ratan, A, Paschal, BM. Genomic analysis of DNA repair genes and androgen signaling in prostate cancer. BMC Cancer. 2018;18 (1):960. doi: 10.1186/s12885-018-4848-x. PubMed PMID:30305041 PubMed Central PMC6180441
  4. Chung, CS, Tsai, CL, Chu, YY, Chen, KC, Lin, JC, Chen, BC, Sun, WC, Yen, HH, Chen, CY, Wu, IC et al.. Clinical features and outcomes of gastric neuroendocrine tumors after endoscopic diagnosis and treatment: A Digestive Endoscopy Society of Tawian (DEST). Medicine (Baltimore). 2018;97 (38):e12101. doi: 10.1097/MD.0000000000012101. PubMed PMID:30235663 PubMed Central PMC6160255
  5. Tu, CH, Yi, HP, Hsieh, SY, Lin, HS, Yang, CS. Overexpression of Different Types of Microbial Rhodopsins with a Highly Expressible Bacteriorhodopsin from Haloarcula marismortui as a Single Protein in E. coli. Sci Rep. 2018;8 (1):14026. doi: 10.1038/s41598-018-32399-x. PubMed PMID:30232361 PubMed Central PMC6145879
  6. Lin, Y, Tsai, SH, Yang, CS, Wu, CH, Huang, CH, Lin, FH, Ku, CH, Chung, CH, Chien, WC, Lai, CY et al.. Improved survival of hospitalized patients with cardiac arrest due to coronary heart disease after implementation of post-cardiac arrest care: A population-based study. Medicine (Baltimore). 2018;97 (37):e12382. doi: 10.1097/MD.0000000000012382. PubMed PMID:30213003
  7. Hsu, HW, Chiu, MC, Shoemaker, D, Yang, CS. Viral infections in fire ants lead to reduced foraging activity and dietary changes. Sci Rep. 2018;8 (1):13498. doi: 10.1038/s41598-018-31969-3. PubMed PMID:30202033 PubMed Central PMC6131164
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Categories: Faculty, Toxicology
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