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Chung “CS” Yang Ph.D.

Distinguished Professor & John L. Colaizzi Endowed Chair in Pharmacy Rutgers University, Ernest Mario School of PharmacyEOHSI – Toxicology
Work William Levine Hall Room 129 160 Frelinghuysen Road Piscataway NJ 08854 Work Phone: 848-445-5360 Work Fax: 732-445-0687
Photo of Chung “CS” Yang Ph.D.

Biographical Info

Research Areas

Mechanisms of carcinogenesis and its prevention, including development of new animal models for colon ad prostate cancers as well as studies on the inhibition of carcinogenesis by tea constituents, tocopherols, and their combination with commonly used drugs. Research is being conducted in animal models, on molecular investigation with cell lines, and in humans.

Research Highlights

  • Development of animal models for colon and prostate cancers using humanized CYP1A mice and PhIP (a dietary carcinogen) to study dietary cancer prevention.
  • Elucidation of the cancer preventive activities and mechanisms of action of green tea polyphenols.
  • Demonstration of the broad cancer prevention activities of tocopherols, especially the higher activity of d-tocopherol than g-tocopherol, and the ineffectiveness of a-tocopherol.
  • Elucidation of the inhibition of the interactions between cancer cells and myeloid derived suppressor cells in vivo and in vitro by curcumin.
  • Conducting translational research on tocopherols in prostate cancer patients.

Scholarly Activities

  • Conduct research as described above.
  • Teach a course on “Diet, Nutrition and Disease Prevention in Pharmacy Practice” and lecture in the course “Molecular Biology and Pharmaceutical Biotechnology.”
  • Serve as a Leader of the Carcinogenesis and Chemoprevention Program of the Cancer Institute of New Jersey.
  • Serve on editorial board of several scientific journals and currently editing a special volume on “Tea and Health” for Pharmacological Research.

Recent Publications

  1. Kamimura, Y, Yang, CS, Lee, CY. Fitness advantages of the biased use of paired laterally symmetrical penises in an insect. J. Evol. Biol. 2019; :. doi: 10.1111/jeb.13486. PubMed PMID:31081978
  2. Hsieh, CF, Yang, CS, Shih, FC, Pan, RP, Pan, CL. Liquid-crystal-based magnetically tunable terahertz achromatic quarter-wave plate. Opt Express. 2019;27 (7):9933-9940. doi: 10.1364/OE.27.009933. PubMed PMID:31045140
  3. Kamata, T, Yang, CS, Jividen, K, Spencer, A, Dworak, N, Oostdyk, LT, Paschal, BM. Detection of ADP-Ribosylation of the Androgen Receptor Using the Recombinant Macrodomain AF1521 from Archaeoglobus fulgidus. Methods Mol. Biol. 2019;1966 :107-124. doi: 10.1007/978-1-4939-9195-2_9. PubMed PMID:31041742
  4. Lin, TL, Chen, YJ, Weng, YC, Yang, CS, Juan, IK. Pityriasis Lichenoid-like Mycosis Fungoides in a 9-year-old Boy: A Case Report. Acta Dermatovenerol Croat. 2019;27 (1):37-39. . PubMed PMID:31032790
  5. Yang, CS, Chen, WD, Gong, GZ, Li, ZJ, Qiu, QT, Yin, Y. [Application of radiomics captured from CT to predict the EGFR mutation status and TKIs therapeutic sensitivity of advanced lung adenocarcinoma]. Zhonghua Zhong Liu Za Zhi. 2019;41 (4):282-287. doi: 10.3760/cma.j.issn.0253-3766.2019.04.007. PubMed PMID:31014053
  6. Hsu, HW, Chiu, MC, Shih, CJ, Matsuura, K, Yang, CS. Apoptosis as a primary defense mechanism in response to viral infection in invasive fire ant Solenopsis invicta. Virology. 2019;531 :255-259. doi: 10.1016/j.virol.2019.03.015. PubMed PMID:30953883
  7. Chen, JL, Lin, YC, Fu, HY, Yang, CS. The Blue-Green Sensory Rhodopsin SRM from Haloarcula marismortui Attenuates Both Phototactic Responses Mediated by Sensory Rhodopsin I and II in Halobacterium salinarum. Sci Rep. 2019;9 (1):5672. doi: 10.1038/s41598-019-42193-y. PubMed PMID:30952934 PubMed Central PMC6450946
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Categories: Faculty, Toxicology
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