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Chung “CS” Yang Ph.D.

Distinguished Professor & John L. Colaizzi Endowed Chair in Pharmacy Rutgers University, Ernest Mario School of PharmacyEOHSI – Toxicology
Work William Levine Hall Room 129 160 Frelinghuysen Road Piscataway NJ 08854 Work Phone: 848-445-5360 Work Fax: 732-445-0687
Photo of Chung “CS” Yang Ph.D.

Biographical Info

Research Areas

Mechanisms of carcinogenesis and its prevention, including development of new animal models for colon ad prostate cancers as well as studies on the inhibition of carcinogenesis by tea constituents, tocopherols, and their combination with commonly used drugs. Research is being conducted in animal models, on molecular investigation with cell lines, and in humans.

Research Highlights

  • Development of animal models for colon and prostate cancers using humanized CYP1A mice and PhIP (a dietary carcinogen) to study dietary cancer prevention.
  • Elucidation of the cancer preventive activities and mechanisms of action of green tea polyphenols.
  • Demonstration of the broad cancer prevention activities of tocopherols, especially the higher activity of d-tocopherol than g-tocopherol, and the ineffectiveness of a-tocopherol.
  • Elucidation of the inhibition of the interactions between cancer cells and myeloid derived suppressor cells in vivo and in vitro by curcumin.
  • Conducting translational research on tocopherols in prostate cancer patients.

Scholarly Activities

  • Conduct research as described above.
  • Teach a course on “Diet, Nutrition and Disease Prevention in Pharmacy Practice” and lecture in the course “Molecular Biology and Pharmaceutical Biotechnology.”
  • Serve as a Leader of the Carcinogenesis and Chemoprevention Program of the Cancer Institute of New Jersey.
  • Serve on editorial board of several scientific journals and currently editing a special volume on “Tea and Health” for Pharmacological Research.

Recent Publications

  1. Liao, CY, Yang, CS, Chen, YJ. Cutaneous neurocristic hamartoma of the scalp: a rare case. Int. J. Dermatol. 2019; :. doi: 10.1111/ijd.14715. PubMed PMID:31721172
  2. Jiao, XF, Lin, XM, Ni, XF, Li, HL, Zhang, C, Yang, CS, Song, HX, Yi, QS, Zhang, LL. Volatile anesthetics versus total intravenous anesthesia in patients undergoing coronary artery bypass grafting: An updated meta-analysis and trial sequential analysis of randomized controlled trials. PLoS ONE. 2019;14 (10):e0224562. doi: 10.1371/journal.pone.0224562. PubMed PMID:31661512 PubMed Central PMC6818786
  3. Mahmood, A, Yang, CS, Jang, S, Routaboul, L, Chang, H, Ghisolfi, A, Braunstein, P, Bernard, L, Verduci, T, Dayen, JF et al.. Tuning graphene transistors through ad hoc electrostatics induced by a nanometer-thick molecular underlayer. Nanoscale. 2019;11 (42):19705-19712. doi: 10.1039/c9nr06407a. PubMed PMID:31620768
  4. Tseng, SP, Wetterer, JK, Suarez, AV, Lee, CY, Yoshimura, T, Shoemaker, D, Yang, CS. Genetic Diversity and Wolbachia Infection Patterns in a Globally Distributed Invasive Ant. Front Genet. 2019;10 :838. doi: 10.3389/fgene.2019.00838. PubMed PMID:31608104 PubMed Central PMC6758599
  5. Yang, CS, Guo, A, Li, Y, Shi, K, Shi, FD, Li, M. Dl-3-n-butylphthalide Reduces Neurovascular Inflammation and Ischemic Brain Injury in Mice. Aging Dis. 2019;10 (5):964-976. doi: 10.14336/AD.2019.0608. PubMed PMID:31595195 PubMed Central PMC6764730
  6. Sun, F, Wang, J, Wu, X, Yang, CS, Zhang, J. Selenium nanoparticles act as an intestinal p53 inhibitor mitigating chemotherapy-induced diarrhea in mice. Pharmacol. Res. 2019;149 :104475. doi: 10.1016/j.phrs.2019.104475. PubMed PMID:31593755
  7. Kim, JS, Kim, YR, Yang, CS. Latest Comprehensive Knowledge of the Crosstalk between TLR Signaling and Mycobacteria and the Antigens Driving the Process. J. Microbiol. Biotechnol. 2019;29 (10):1506-1521. doi: 10.4014/jmb.1908.08057. PubMed PMID:31581380
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Categories: Faculty, Toxicology
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