Robert Laumbach M.D., M.P.H., C.I.H.
Current research interests are focused on two areas: 1) the interactive effects of exposure to multiple air pollutants and psychosocial stressors, and their cumulative impact on urban disparities in asthma, heart disease and cancer and 2) biological mechanisms underlying the effects of diesel exhaust and other air pollutants on pulmonary and cardiovascular disease. Approaches include community-based participatory research, controlled exposure studies, and semi-controlled “real-world” environmental exposure studies.
Using controlled exposure to study interactions between exposure to diesel exhaust and psychological stress, we demonstrated that diesel exhaust can cause systemic “sickness response symptoms” in young healthy adults
Using controlled exposure, we demonstrated that 1-aminopyrene may be a useful, specific biomarker for exposure to diesel exhaust.
A simulated commuter car ride caused changes in cardiovascular function among volunteers with diabetes, measured as a decrease in heart rate variability at 24 hours after the ride
Exposure to plume of dust and smoke from the 9/11 World Trade Center disaster was not associated with increased respiratory symptoms outside of the lower Manhattan area
Development of collaborative relationships with stakeholders interested in applying scientific principles and knowledge to mitigate the environmental health problems and injustices in urban communities and communities adjacent to seaports in New Jersey.
Promotion of science in public health policy in New Jersey through service on the New Jersey Department of Environmental Protection Science Advisory Board and New Jersey Clean Air Council.
Laumbach RJ, Kipen HM. Bioaerosols and sick building syndrome: particles, inflammation and allergy. Current Opinion in Allergy and Clinical Immunology: 5(2):135-9. 2005
Laumbach RJ, Fiedler N, Gardner CR, Laskin DL, Fan ZH, Zhang J, Weschler CJ, Lioy PJ, Devlin RB, Ohman-Strickland P, Kelly-McNeil K, Kipen HM. Nasal effects of a mixture of volatile organic compounds and their ozone oxidation products. Journal of Occupational and Environmental Medicine. 47:1182-1189. 2005.
Fiedler N, Laumbach RJ, Kelly-McNeil K, Lioy PJ, Fan ZH, Zhang J, Ottenweller J, Ohman-Strickland P, , Kipen HM. Health effects of a mixture of indoor air volatile organics, their ozone oxidation products and stress. Environmental Health Perspectives. 1139(11)1542-8, 2005.
Sunil V, Laumbach RJ, Patel K, Turpin BJ, Lim HJ, Kipen HM, Laskin J, Laskin DL. Pulmonary Effects of Inhaled Limonene Ozone Reaction Products in Elderly Rats. Toxicology and Applied Pharmacology. 222 (2), 211-220. 2007.
Laumbach R, Tong J, Zhang L, Ohman-Strickland P, Stern A, Fiedler N, Kipen H, Kelly-McNeil K, Lioy P, Zhang J. Quantification of 1-aminopyrene in human urine after a controlled exposure to diesel exhaust. Journal of Environmental Monitoring. 11(1):153-9, 2009.
Laumbach RL, Harris G, Kipen HM, Georgopoulos P, Shade P, Isukapalli S, Galea S, Vlahov D, Wartenberg D. Lack of association between estimated WTC plume intensity and respiratory symptoms among residents outside of Lower Manhattan. American Journal of Epidemiology. 170(5):640-9, 2009.
Laumbach RL. Air pollution and patient health. American Family Physician. 81 (2):175-180, January 15, 2010.
Laumbach RJ, Rich DQ, Gandhi S, Amorosa L, Schneider S, Zhang J, Ohman-Strickland P, Gong J, Lelyanov O, Kipen HM. Acute changes in heart rate variability in subjects with diabetes following a highway traffic exposure. J. of Occupational and Environmental Medicine, 52 (3), 2010.
Laumbach RJ, Kipen HM. Acute effects of motor vehicle traffic-related air pollution exposures on measures of oxidative stress. Ann. N.Y. Acad. Sci. 1203; 107-112, 2010
Laumbach RJ, Kipen HM, Kelly-McNeil K, Zhang L, Lioy PJ, Ohman-Strickland P, Gong J, Kusnecov A, Fiedler N. (2011) Sickness response symptoms among healthy volunteers after controlled exposures to diesel exhaust and psychological stress. (Epub ahead of print) Environmental Health Perspectives PMID: 21330231